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Method development and testing for bioaccessibility of metals
Bioaccessibility of metals in powdered alloys and metal ores: Evaluation of three surrogate biofluids
One of our metal bioaccessibility studies evaluates differences in the exposure dose of metals in alloys by measuring and evaluating metal bioaccessibility from several economically important grades of alloy powders exposed to physiologically based in vitro tests incorporating human surrogate biofluids representing three major exposure routes; ingestion, inhalation and dermal. The robustness of the test is evaluated using standard reference materials (SRMs) by systematically modifying key experimental conditions that are currently not standardized. The results demonstrate that the in vitro bioaccessibility test is ideally capable in evaluating intrinsic differences of uniquely different alloy grades for health characterization purposes.
Nickel Beyond Environmental Exposure: Stainless Steel Cookware's Contribution to Nickel Exposure from Cooked Foods
Nickel may be introduced to the diet via leaching from stainless steel cookware into foods during cooking processes, contributing to flare-ups of allergic contact dermatitis. We are testing variables grade of stainless steel, cook time, and repeated usage or cooking cycles, for their effect on nickel in cooked foods.
Hillwalker, WE, Anderson, KA,Bioaccessibility of metals in alloys: evaluation of three surrogate biofluids., Environ. Pollut. 2014, 185(), 52-8
Kamerud, KL, Hobbie, KA, Anderson, KA,Stainless steel leaches nickel and chromium into foods during cooking., J. Agric. Food Chem. 2013, 61(39), 9495-501
Henderson, R, Verougstraete, V, Anderson, KA, Arbildua, J, Brock, T, Brouwers, T, Cappellini, D, Delbeke, K,Inter-Laboratory Validation of Bioaccessibility Test for Metals, 2014, Society of Toxicology 53rd Annual Meeting, Phoenix, AZ
Hobbie, KA, Kamerud, KL, Anderson, KA,Stainless Steel Leaches Nickel and Chromium into Foods During Cooking., 2014, Society of Toxicology 53rd Annual Meeting, Phoenix, AZ
Kamerud, KL, Hobbie, KA, Anderson, KA,Nickel Beyond Environmental Exposure: Stainless Steel Cookware's Contribution to Nickel Exposure from Cooked Foods, 2012, SETAC North America 33rd Annual Meeting