<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Nelson, Isabella M</style></author><author><style face="normal" font="default" size="100%">Vazquez, Joana Hernandez</style></author><author><style face="normal" font="default" size="100%">Poutasse, Carolyn M</style></author><author><style face="normal" font="default" size="100%">Adams, Kaley T</style></author><author><style face="normal" font="default" size="100%">O&#039;Connell, Steven G</style></author><author><style face="normal" font="default" size="100%">Smith, Brian W</style></author><author><style face="normal" font="default" size="100%">Herbstman, Julie B</style></author><author><style face="normal" font="default" size="100%">Raessler, Jana M</style></author><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Unraveling the environmental links to feline hyperthyroidism: Insights from silicone passive samplers.</style></title><secondary-title><style face="normal" font="default" size="100%">Environ Res</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Environ Res</style></alt-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Animals</style></keyword><keyword><style  face="normal" font="default" size="100%">Cat Diseases</style></keyword><keyword><style  face="normal" font="default" size="100%">Cats</style></keyword><keyword><style  face="normal" font="default" size="100%">Endocrine Disruptors</style></keyword><keyword><style  face="normal" font="default" size="100%">Environmental Exposure</style></keyword><keyword><style  face="normal" font="default" size="100%">Environmental Monitoring</style></keyword><keyword><style  face="normal" font="default" size="100%">Environmental Pollutants</style></keyword><keyword><style  face="normal" font="default" size="100%">Female</style></keyword><keyword><style  face="normal" font="default" size="100%">Flame Retardants</style></keyword><keyword><style  face="normal" font="default" size="100%">Hyperthyroidism</style></keyword><keyword><style  face="normal" font="default" size="100%">Male</style></keyword><keyword><style  face="normal" font="default" size="100%">New York</style></keyword><keyword><style  face="normal" font="default" size="100%">Silicones</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2025</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2025 Dec 01</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">286</style></volume><pages><style face="normal" font="default" size="100%">122885</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;Feline hyperthyroidism (FH) is the most common endocrine disorder affecting cats and poses significant health challenges to domestic cats and veterinary professionals. This disease is caused by the effects of excess thyroid hormone production and causes a variety of symptoms including weight loss, increased urination, and increased appetite. Despite its prevalence, the underlying cause of this condition remains unclear. While many factors have been extensively studied, there isn&#039;t conclusive evidence linking hyperthyroidism to diet, litter, and indoor lifestyle. Recent research has suggested an association between FH and exposure to flame retardants in consumer products. Many consumer products also contain other endocrine-disrupting chemicals (EDCs) and potential endocrine-disrupting chemicals (pEDCs) in addition to flame retardants that could be linked to FH. To investigate this further, silicone passive sampling devices (PSDs) in the form of pet tags were used to measure the environmental chemical exposure of 78 cats, aged seven years and older, in Oregon and New York using a chemical screening method containing hundreds of EDCs/pEDCs. The objective of this study was to compare exposure frequencies and concentrations between hyperthyroid and non-hyperthyroid cats. While no statistically significant associations were identified, this study found higher concentrations of butyl benzyl phthalate (BBP), galaxolide, lilial, and tonalide in the tags worn by cats with FH compared to euthyroid cats. TCPP, b-ionone, lilial, cinnamal, benzyl salicylate, and tonalide have not been previously mentioned in past feline exposure studies. These chemicals are found in various personal care and consumer products such as vinyl tiles, fragrances, furniture, and cosmetics. Their presence in PSDs worn by cats that develop hyperthyroidism may indicate a potential role of these environmental chemicals in FH etiology.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">Pt 2</style></issue></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Carolyn M Poutasse</style></author><author><style face="normal" font="default" size="100%">Julie Herbstman</style></author><author><style face="normal" font="default" size="100%">Mark E Peterson</style></author><author><style face="normal" font="default" size="100%">Jana Gordon</style></author><author><style face="normal" font="default" size="100%">Peter Soboroff</style></author><author><style face="normal" font="default" size="100%">Darrell Holmes</style></author><author><style face="normal" font="default" size="100%">Dezere Gonzalez</style></author><author><style face="normal" font="default" size="100%">Lane G Tidwell</style></author><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Silicone Pet Tags Associate Tris(1,3-dichloro-2-isopropyl) Phosphate Exposures with Feline Hyperthyroidism.</style></title><secondary-title><style face="normal" font="default" size="100%">Environ Sci Technol</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Environ Sci Technol</style></alt-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Animals</style></keyword><keyword><style  face="normal" font="default" size="100%">Cats</style></keyword><keyword><style  face="normal" font="default" size="100%">Flame Retardants</style></keyword><keyword><style  face="normal" font="default" size="100%">Halogenated Diphenyl Ethers</style></keyword><keyword><style  face="normal" font="default" size="100%">Hyperthyroidism</style></keyword><keyword><style  face="normal" font="default" size="100%">New York</style></keyword><keyword><style  face="normal" font="default" size="100%">Oregon</style></keyword><keyword><style  face="normal" font="default" size="100%">Organophosphates</style></keyword><keyword><style  face="normal" font="default" size="100%">Phosphates</style></keyword><keyword><style  face="normal" font="default" size="100%">Silicones</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2019 Aug 06</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">53</style></volume><pages><style face="normal" font="default" size="100%">9203-9213</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;Feline hyperthyroidism is the most commonly diagnosed endocrine-related disease among senior and geriatric housecats, but the causes remain unknown. Exposure to endocrine-disrupting compounds with thyroid targets, such as flame retardants (FRs), may contribute to disease development. Silicone passive sampling devices, or pet tags, quantitatively assessed the bioavailable FR exposures of 78 cats (≥7 y) in New York and Oregon using gas chromatography-mass spectrometry. Pet tags were analyzed for 36 polybrominated diphenyl ethers, six organophosphate esters (OPEs), and two alternative brominated FRs. In nonhyperthyroid cats, serum free thyroxine (fT), total T (TT), total triiodothyronine, and thyroid-stimulating hormone concentrations were compared with FR concentrations. Tris(1,3-dichloro-2-isopropyl) phosphate (TDCIPP) concentrations were higher in hyperthyroid pet tags in comparison to nonhyperthyroid pet tags (adjusted odds ratio, &amp;lt; 0.07; Mantel-Cox, &amp;lt; 0.02). Higher TDCIPP concentrations were associated with air freshener use in comparison to no use ( &amp;lt; 0.01), residences built since 2005 compared to those pre-1989 ( &amp;lt; 0.002), and cats preferring to spend time on upholstered furniture in comparison to no preference ( &amp;lt; 0.05). Higher TDCIPP concentrations were associated with higher fT and TT concentrations ( &amp;lt; 0.05). This study provides proof-of-concept data for the use of silicone pet tags with companion animals and further indicates that bioavailable TDCIPP exposures are associated with feline hyperthyroidism.&lt;/p&gt;
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