<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Kathleen Mullen</style></author><author><style face="normal" font="default" size="100%">Briana N Rivera</style></author><author><style face="normal" font="default" size="100%">Lane G Tidwell</style></author><author><style face="normal" font="default" size="100%">Renata Ivanek</style></author><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author><author><style face="normal" font="default" size="100%">Dorothy Ainsworth</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Environmental surveillance and adverse neonatal health outcomes in foals born near unconventional natural gas development activity.</style></title><secondary-title><style face="normal" font="default" size="100%">Sci Total Environ</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Sci. Total Environ.</style></alt-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Animals</style></keyword><keyword><style  face="normal" font="default" size="100%">Animals, Newborn</style></keyword><keyword><style  face="normal" font="default" size="100%">Environmental Monitoring</style></keyword><keyword><style  face="normal" font="default" size="100%">Female</style></keyword><keyword><style  face="normal" font="default" size="100%">Horses</style></keyword><keyword><style  face="normal" font="default" size="100%">Humans</style></keyword><keyword><style  face="normal" font="default" size="100%">Infant, Newborn</style></keyword><keyword><style  face="normal" font="default" size="100%">Male</style></keyword><keyword><style  face="normal" font="default" size="100%">Natural Gas</style></keyword><keyword><style  face="normal" font="default" size="100%">New York</style></keyword><keyword><style  face="normal" font="default" size="100%">Outcome Assessment, Health Care</style></keyword><keyword><style  face="normal" font="default" size="100%">Pennsylvania</style></keyword><keyword><style  face="normal" font="default" size="100%">Pregnancy</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2020 Aug 20</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">731</style></volume><pages><style face="normal" font="default" size="100%">138497</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;Studies of neonatal health risks of unconventional natural gas development (UNGD) have not included comprehensive assessments of environmental chemical exposures. We investigated a clustering of dysphagic cases in neonatal foals born between 2014 and 2016 in an area of active UNGD in Pennsylvania (PA),USA. We evaluated equine biological data and environmental exposures on the affected PA farm and an unaffected New York (NY) farm owned by the same proprietor. Dams either spent their entire gestation on one farm or moved to the other farm in late gestation. Over the 21-month study period, physical examinations and blood/tissue samples were obtained from mares and foals on each farm. Grab samples of water, pasture soil and feed were collected; continuous passive sampling of air and water for polycyclic aromatic hydrocarbons was performed. Dysphagia was evaluated as a binary variable; logistic regression was used to identify risk factors. Sixty-five foals were born, 17 (all from PA farm) were dysphagic. Odds of dysphagia increased with the dam residing on the PA farm for each additional month of gestation (OR&amp;nbsp;=&amp;nbsp;1.4, 95% CI 1.2, 1.7, p&amp;nbsp;=&amp;nbsp;6.0E-04). Males were more likely to be born dysphagic (OR&amp;nbsp;=&amp;nbsp;5.5, 95% CI 1.2, 24.5, p&amp;nbsp;=&amp;nbsp;0.03) than females. Prior to installation of a water filtration/treatment system, PA water concentrations of 3,6-dimethylphenanthrene (p&amp;nbsp;=&amp;nbsp;6.0E-03), fluoranthene (p&amp;nbsp;=&amp;nbsp;0.03), pyrene (p&amp;nbsp;=&amp;nbsp;0.02) and triphenylene (p&amp;nbsp;=&amp;nbsp;0.01) exceeded those in NY water. Compared to NY farm water, no concentrations of PAHs were higher in PA following installation of the water filtration/treatment system. We provide evidence of an uncommon adverse health outcome (dysphagia) in foals born near UNGD that was eliminated in subsequent years (2017-2019) following environmental management changes. Notably, this study demonstrates that domestic large animals such as horses can serve as important sentinels for human health risks associated with UNGD activities.&lt;/p&gt;
</style></abstract></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Paulik, L Blair</style></author><author><style face="normal" font="default" size="100%">Kevin A Hobbie</style></author><author><style face="normal" font="default" size="100%">Diana Rohlman</style></author><author><style face="normal" font="default" size="100%">Brian W Smith</style></author><author><style face="normal" font="default" size="100%">Richard P Scott</style></author><author><style face="normal" font="default" size="100%">Laurel D Kincl</style></author><author><style face="normal" font="default" size="100%">Erin N Haynes</style></author><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Environmental and individual PAH exposures near rural natural gas extraction.</style></title><secondary-title><style face="normal" font="default" size="100%">Environ Pollut</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Environ. Pollut.</style></alt-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Air Pollutants</style></keyword><keyword><style  face="normal" font="default" size="100%">Air Pollution</style></keyword><keyword><style  face="normal" font="default" size="100%">Environmental Exposure</style></keyword><keyword><style  face="normal" font="default" size="100%">Environmental Monitoring</style></keyword><keyword><style  face="normal" font="default" size="100%">Humans</style></keyword><keyword><style  face="normal" font="default" size="100%">Linear Models</style></keyword><keyword><style  face="normal" font="default" size="100%">Natural Gas</style></keyword><keyword><style  face="normal" font="default" size="100%">Oil and Gas Fields</style></keyword><keyword><style  face="normal" font="default" size="100%">Petroleum</style></keyword><keyword><style  face="normal" font="default" size="100%">Polycyclic Aromatic Hydrocarbons</style></keyword><keyword><style  face="normal" font="default" size="100%">Pyrenes</style></keyword><keyword><style  face="normal" font="default" size="100%">Silicones</style></keyword><keyword><style  face="normal" font="default" size="100%">Tandem Mass Spectrometry</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2018 Oct</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">241</style></volume><pages><style face="normal" font="default" size="100%">397-405</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;Natural gas extraction (NGE) has expanded rapidly in the United States in recent years. Despite concerns, there is little information about the effects of NGE on air quality or personal exposures of people living or working nearby. Recent research suggests NGE emits polycyclic aromatic hydrocarbons (PAHs) into air. This study used low-density polyethylene passive samplers to measure concentrations of PAHs in air near active (n = 3) and proposed (n = 2) NGE sites. At each site, two concentric rings of air samplers were placed around the active or proposed well pad location. Silicone wristbands were used to assess personal PAH exposures of participants (n = 19) living or working near the sampling sites. All samples were analyzed for 62 PAHs using GC-MS/MS, and point sources were estimated using the fluoranthene/pyrene isomer ratio. ∑PAH was significantly higher in air at active NGE sites (Wilcoxon rank sum test, p &amp;lt; 0.01). PAHs in air were also more petrogenic (petroleum-derived) at active NGE sites. This suggests that PAH mixtures at active NGE sites may have been affected by direct emissions from petroleum sources at these sites. ∑PAH was also significantly higher in wristbands from participants who had active NGE wells on their properties than from participants who did not (Wilcoxon rank sum test, p &amp;lt; 0.005). There was a significant positive correlation between ∑PAH in participants&#039; wristbands and ∑PAH in air measured closest to participants&#039; homes or workplaces (simple linear regression, p &amp;lt; 0.0001). These findings suggest that living or working near an active NGE well may increase personal PAH exposure. This work also supports the utility of the silicone wristband to assess personal PAH exposure.&lt;/p&gt;
</style></abstract></record></records></xml>