<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Steven G O&#039;Connell</style></author><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author><author><style face="normal" font="default" size="100%">Epstein, Marc I</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Determining chemical air equivalency using silicone personal monitors.</style></title><secondary-title><style face="normal" font="default" size="100%">J Expo Sci Environ Epidemiol</style></secondary-title><alt-title><style face="normal" font="default" size="100%">J Expo Sci Environ Epidemiol</style></alt-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Air Pollutants</style></keyword><keyword><style  face="normal" font="default" size="100%">Environmental Monitoring</style></keyword><keyword><style  face="normal" font="default" size="100%">Humans</style></keyword><keyword><style  face="normal" font="default" size="100%">Silicones</style></keyword><keyword><style  face="normal" font="default" size="100%">Volatile Organic Compounds</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2022 03</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">32</style></volume><pages><style face="normal" font="default" size="100%">268-279</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;BACKGROUND: &lt;/strong&gt;Silicone personal samplers are increasingly being used to measure chemical exposures, but many of these studies do not attempt to calculate environmental concentrations.&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;OBJECTIVE: &lt;/strong&gt;Using measurements of silicone wristband uptake of organic chemicals from atmospheric exposure, create log K and k predictive models based on empirical data to help develop air equivalency calculations for both volatile and semi-volatile organic compounds.&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;METHODS: &lt;/strong&gt;An atmospheric vapor generator and a custom exposure chamber were used to measure the uptake of organic chemicals into silicone wristbands under simulated indoor conditions. Log K models were evaluated using repeated k-fold cross-validation. Air equivalency was compared between best-performing models.&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;RESULTS: &lt;/strong&gt;Log K and log k estimates calculated from uptake data were used to build predictive models from boiling point (BP) and other parameters (all models: R = 0.70-0.94). The log K models were combined with published data and refined to create comprehensive and effective predictive models (R: 0.95-0.97). Final estimates of air equivalency using novel BP models correlated well over an example dataset (Spearman r = 0.984) across 5-orders of magnitude (&amp;lt;0.05 to &amp;gt;5000 ng/L).&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;SIGNIFICANCE: &lt;/strong&gt;Data from silicone samplers can be translated into air equivalent concentrations that better characterize environmental concentrations associated with personal exposures and allow direct comparisons to regulatory levels.&lt;/p&gt;
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