<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Soni, Monica</style></author><author><style face="normal" font="default" size="100%">Chen, Haiying</style></author><author><style face="normal" font="default" size="100%">Cepeda, Milton J</style></author><author><style face="normal" font="default" size="100%">Berenson, Lesley</style></author><author><style face="normal" font="default" size="100%">Smith, Sydney</style></author><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author><author><style face="normal" font="default" size="100%">Quandt, Sara A</style></author><author><style face="normal" font="default" size="100%">Arcury, Thomas A</style></author><author><style face="normal" font="default" size="100%">Laurienti, Paul J</style></author><author><style face="normal" font="default" size="100%">Burdette, Jonathan H</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">A longitudinal study comparing the impact of pesticide exposure on cognitive abilities of Latinx children from rural farmworker and urban non-farmworker families.</style></title><secondary-title><style face="normal" font="default" size="100%">Neurotoxicol Teratol</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Neurotoxicol Teratol</style></alt-title></titles><dates><year><style  face="normal" font="default" size="100%">2025</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2025 Apr 13</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">109</style></volume><pages><style face="normal" font="default" size="100%">107450</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;Growing evidence shows that pesticide exposure contributes to numerous adverse health effects. Pesticide exposure can be especially problematic for vulnerable populations, and even more so for children in vulnerable populations who are still developing, such as Latinx children. Several studies have demonstrated the negative cognitive effects of prenatal exposure to pesticides, particularly organophosphates (OPs). We previously reported the results from a baseline study (Dobbins et al., 2022) designed to compare the cognitive abilities of 8-year-old children from rural, farmworking families and urban, non-farmworking families. We found that the children from both populations have considerable pesticide exposure, but to different chemicals. The children of farmworkers had greater exposure to OPs, while the children of non-farmworkers had greater exposure to organochlorines (OCs) and pyrethroids. Using the Weschler Intelligence Scale for Children-Fifth Edition (WISC-V), baseline analyses determined that children of non-farmworkers exhibited lower cognitive scores, specifically on the VSI (visual spatial) and VCI (verbal comprehension) indices. The current study examined the longitudinal significance of these findings in the same participants over a 2-3-year period. We present evidence that children from non-farmworking families exhibited significant declines on the FRI (fluid reasoning index) of the WISC-V. The children from farmworker families did not decline, and this longitudinal difference between the groups was significant. Our findings further suggest that these declines in FRI scores are likely due to greater cumulative OC exposure over the entire longitudinal period.&lt;/p&gt;
</style></abstract></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Lepetit, Cassandra</style></author><author><style face="normal" font="default" size="100%">Gaber, Mohamed</style></author><author><style face="normal" font="default" size="100%">Zhou, Ke</style></author><author><style face="normal" font="default" size="100%">Chen, Haiying</style></author><author><style face="normal" font="default" size="100%">Holmes, Julia</style></author><author><style face="normal" font="default" size="100%">Summers, Phillip</style></author><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author><author><style face="normal" font="default" size="100%">Scott, Richard P</style></author><author><style face="normal" font="default" size="100%">Pope, Carey N</style></author><author><style face="normal" font="default" size="100%">Hester, Kirstin</style></author><author><style face="normal" font="default" size="100%">Laurienti, Paul J</style></author><author><style face="normal" font="default" size="100%">Quandt, Sara A</style></author><author><style face="normal" font="default" size="100%">Arcury, Thomas A</style></author><author><style face="normal" font="default" size="100%">Vidi, Pierre-Alexandre</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Follicular DNA Damage and Pesticide Exposure Among Latinx Children in Rural and Urban Communities.</style></title><secondary-title><style face="normal" font="default" size="100%">Expo Health</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Expo Health</style></alt-title></titles><dates><year><style  face="normal" font="default" size="100%">2024</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2024</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">16</style></volume><pages><style face="normal" font="default" size="100%">1039-1052</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;UNLABELLED: &lt;/strong&gt;The intersectional risks of children in United States immigrant communities include environmental exposures. Pesticide exposures and their biological outcomes are not well characterized in this population group. We assessed pesticide exposure and related these exposures to DNA double-strand breaks (DSBs) in Latinx children from rural, farmworker families (FW;  = 30) and from urban, non-farmworker families (NFW;  = 15) living in North Carolina. DSBs were quantified in hair follicular cells by immunostaining of 53BP1, and exposure to 72 pesticides and pesticide degradation products were determined using silicone wristbands. Cholinesterase activity was measured in blood samples. DSB frequencies were higher in FW compared to NFW children. Seasonal effects were detected in the FW group, with highest DNA damage levels in April-June and lowest levels in October-November. Acetylcholinesterase depression had the same seasonality and correlated with follicular DNA damage. Organophosphate pesticides were more frequently detected in FW than in NFW children. Participants with organophosphate detections had increased follicular DNA damage compared to participants without organophosphate detection. Follicular DNA damage did not correlate with organochlorine or pyrethroid detections and was not associated with the total number of pesticides detected in the wristbands. These results point to rural disparities in pesticide exposures and their outcomes in children from vulnerable immigrant communities. They suggest that among the different classes of pesticides, organophosphates have the strongest genotoxic effects. Assessing pesticide exposures and their consequences at the individual level is key to environmental surveillance programs. To this end, the minimally invasive combined approach used here is particularly well suited for children.&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;SUPPLEMENTARY INFORMATION: &lt;/strong&gt;The online version contains supplementary material available at 10.1007/s12403-023-00609-1.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Sara A Quandt</style></author><author><style face="normal" font="default" size="100%">Smith, Sydney A</style></author><author><style face="normal" font="default" size="100%">Thomas A Arcury</style></author><author><style face="normal" font="default" size="100%">Haiying Chen</style></author><author><style face="normal" font="default" size="100%">Kirstin Hester</style></author><author><style face="normal" font="default" size="100%">Carey N Pope</style></author><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author><author><style face="normal" font="default" size="100%">Paul J Laurienti</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Comparing Longitudinal Measures of Cholinesterase as Biomarkers for Insecticide Exposure Among Latinx Children in Rural Farmworker and Urban Non-Farmworker Communities in North Carolina.</style></title><secondary-title><style face="normal" font="default" size="100%">J Occup Environ Med</style></secondary-title><alt-title><style face="normal" font="default" size="100%">J Occup Environ Med</style></alt-title></titles><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2023 Sep 06</style></date></pub-dates></dates><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;OBJECTIVE: &lt;/strong&gt;In a two-group prospective design, this study compares seasonal cholinesterase levels of Latinx children in rural farmworker families and comparable urban children, to assess the impact of environmental exposure to cholinesterase-inhibiting insecticides.&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;METHODS: &lt;/strong&gt;Quarterly blood samples and passive dosimeter wristbands were collected over 2 years in 8 year old children (74 rural, 62 urban). Laboratory analysis assessed total cholinesterase (total ChE), acetylcholinesterase (AChE), and butyrylcholinesterase (BChE) from blood samples, and insecticides from wristbands.&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;RESULTS: &lt;/strong&gt;In spring and summer, total ChE and AChE levels were depressed in rural children compared to winter and fall. BChE was depressed in rural children in fall, compared to spring and summer. Adjustment for insecticide exposure did not affect these associations.&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;CONCLUSIONS: &lt;/strong&gt;Environmental exposures to cholinesterase-inhibiting insecticides have measurable biochemical effects on blood cholinesterases in rural children from farmworker families.&lt;/p&gt;
</style></abstract></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Cassandra Lepetit</style></author><author><style face="normal" font="default" size="100%">Mohamed Gaber</style></author><author><style face="normal" font="default" size="100%">Ke Zhou</style></author><author><style face="normal" font="default" size="100%">Haiying Chen</style></author><author><style face="normal" font="default" size="100%">Julia Holmes</style></author><author><style face="normal" font="default" size="100%">Phillip Summers</style></author><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author><author><style face="normal" font="default" size="100%">Richard P Scott</style></author><author><style face="normal" font="default" size="100%">Carey N Pope</style></author><author><style face="normal" font="default" size="100%">Kirstin Hester</style></author><author><style face="normal" font="default" size="100%">Paul J Laurienti</style></author><author><style face="normal" font="default" size="100%">Sara A Quandt</style></author><author><style face="normal" font="default" size="100%">Thomas A Arcury</style></author><author><style face="normal" font="default" size="100%">Pierre‑Alexandre Vidi</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Follicular DNA Damage and Pesticide Exposure Among Latinx Children in Rural and Urban Communities</style></title></titles><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">09/2023</style></date></pub-dates></dates><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;The intersectional risks of children in United States immigrant communities include environmental exposures. Pesticide exposures and their biological outcomes are not well characterized in this population group. We assessed pesticide exposure and related these exposures to DNA double-strand breaks (DSBs) in Latinx children from rural, farmworker families (FW; N = 30) and from urban, non-farmworker families (NFW; N = 15) living in North Carolina. DSBs were quantified in hair follicular cells by immunostaining of 53BP1, and exposure to 72 pesticides and pesticide degradation products were determined using silicone wristbands. Cholinesterase activity was measured in blood samples. DSB frequencies were higher in FW compared to NFW children. Seasonal effects were detected in the FW group, with highest DNA damage levels in April–June and lowest levels in October–November. Acetylcholinesterase depression had the same seasonality and correlated with follicular DNA damage. Organophosphate pesticides were more frequently detected in FW than in NFW children. Participants with organophosphate detections had increased follicular DNA damage compared to participants without organophosphate detection. Follicular DNA damage did not correlate with organochlorine or pyrethroid detections and was not associated with the total number of pesticides detected in the wristbands. These results point to rural disparities in pesticide exposures and their outcomes in children from vulnerable immigrant communities. They suggest that among the different classes of pesticides, organophosphates have the strongest genotoxic effects. Assessing pesticide exposures and their consequences at the individual level is key to environmental surveillance programs. To this end, the minimally invasive combined approach used here is particularly well suited for children.&lt;/p&gt;
</style></abstract></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Monica L. Vermillion Maier</style></author><author><style face="normal" font="default" size="100%">Siddens, Lisbeth K</style></author><author><style face="normal" font="default" size="100%">Jamie Pennington</style></author><author><style face="normal" font="default" size="100%">Sandra Uesugi</style></author><author><style face="normal" font="default" size="100%">Labut, Edwin M</style></author><author><style face="normal" font="default" size="100%">Vertel, Emily A</style></author><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author><author><style face="normal" font="default" size="100%">Lane G Tidwell</style></author><author><style face="normal" font="default" size="100%">Susan C Tilton</style></author><author><style face="normal" font="default" size="100%">Ted J Ognibene</style></author><author><style face="normal" font="default" size="100%">Kenneth Turteltaub</style></author><author><style face="normal" font="default" size="100%">Jordan Smith</style></author><author><style face="normal" font="default" size="100%">Williams, David E</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Impact of phenanthrene co-administration on the toxicokinetics of benzo[a]pyrene in humans. UPLC-accelerator mass spectrometry following oral microdosing.</style></title><secondary-title><style face="normal" font="default" size="100%">Chem Biol Interact</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Chem Biol Interact</style></alt-title></titles><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2023 Jun 25</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">382</style></volume><pages><style face="normal" font="default" size="100%">110608</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;Current risk assessments for environmental carcinogens rely on animal studies utilizing doses orders of magnitude higher than actual human exposures. Epidemiological studies of people with high exposures (e.g., occupational) are of value, but rely on uncertain exposure data. In addition, exposures are typically not to a single chemical but to mixtures, such as polycyclic aromatic hydrocarbons (PAHs). The extremely high sensitivity of accelerator mass spectrometry (AMS) allows for dosing humans with known carcinogens with de minimus risk. In this study UPLC-AMS was used to assess the toxicokinetics of [C]-benzo[a]pyrene ([C]-BaP) when dosed alone or in a binary mixture with phenanthrene (Phe). Plasma was collected for 48&amp;nbsp;h following a dose of [C]-BaP (50&amp;nbsp;ng, 5.4&amp;nbsp;nCi) or the same dose of [C]-BaP plus Phe (1250&amp;nbsp;ng). Following the binary mixture, C of [C]-BaP significantly decreased (4.4-fold) whereas the volume of distribution (V) increased (2-fold). Further, the toxicokinetics of twelve [C]-BaP metabolites provided evidence of little change in the metabolite profile of [C]-BaP and the pattern was overall reduction consistent with reduced absorption (decrease in C). Although Phe was shown to be a competitive inhibitor of the major hepatic cytochrome P-450 (CYP) responsible for metabolism of [C]-BaP, CYP1A2, the high inhibition constant (K) and lack of any increase in unmetabolized [C]-BaP in plasma makes this mechanism unlikely to be responsible. Rather, co-administration of Phe reduces the absorption of [C]-BaP through a mechanism yet to be determined. This is the first study to provide evidence that, at actual environmental levels of exposure, the toxicokinetics of [C]-BaP in humans is markedly altered by the presence of a second PAH, Phe, a common component of environmental PAH mixtures.&lt;/p&gt;
</style></abstract></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Khodaei, Mohammadreza</style></author><author><style face="normal" font="default" size="100%">Dobbins, Dorothy L</style></author><author><style face="normal" font="default" size="100%">Paul J Laurienti</style></author><author><style face="normal" font="default" size="100%">Simpson, Sean L</style></author><author><style face="normal" font="default" size="100%">Thomas A Arcury</style></author><author><style face="normal" font="default" size="100%">Sara A Quandt</style></author><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author><author><style face="normal" font="default" size="100%">Richard P Scott</style></author><author><style face="normal" font="default" size="100%">Jonathan H Burdette</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Neuroanatomical differences in Latinx children from rural farmworker families and urban non-farmworker families and related associations with pesticide exposure.</style></title><secondary-title><style face="normal" font="default" size="100%">Heliyon</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Heliyon</style></alt-title></titles><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2023 Nov</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">9</style></volume><pages><style face="normal" font="default" size="100%">e21929</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;Exposure to pesticides in humans may lead to changes in brain structure and function and increase the likelihood of experiencing neurodevelopmental disorders. Despite the potential risks, there is limited neuroimaging research on the effects of pesticide exposure on children, particularly during the critical period of brain development. Here we used voxel-based morphometry (VBM) and diffusion tensor imaging (DTI) from magnetic resonance images (MRI) to investigate neuroanatomical differences between Latinx children (n&amp;nbsp;=&amp;nbsp;71) from rural, farmworker families (FW; n&amp;nbsp;=&amp;nbsp;48) and urban, non-farmworker families (NFW; n&amp;nbsp;=&amp;nbsp;23). Data presented here serves as a baseline for our ongoing study examining the longitudinal effects of living in a rural environment on neurodevelopment and cognition in children. The VBM analysis revealed that NFW children had higher volume in several distinct regions of white matter compared to FW children. Tract-based spatial statistics (TBSS) of DTI data also indicated NFW children had higher fractional anisotropy (FA) in several key white matter tracts. Although the difference was not as pronounced as white matter, the VBM analysis also found higher gray matter volume in selected regions of the frontal lobe in NFW children. Notably, white matter and gray matter findings demonstrated a high degree of overlap in the medial frontal lobe, a brain region predominantly linked to decision-making, error processing, and attention functions. To gain further insights into the underlying causes of the observed differences in brain structure between the two groups, we examined the association of organochlorine (OC) and organophosphate (OP) exposure collected from passive dosimeter wristbands with brain structure. Based on our previous findings within this data set, demonstrating higher OC exposure in children from non-farmworker families, we hypothesized OC might play a critical role in structural differences between NFW and FW children. We discovered a significant positive correlation between the number of types of OC exposure and the structure of white matter. The regions with significant association with OC exposure were in agreement with the findings from the FW-NFW groups comparison analysis. In contrast, OPs did not have a statistically significant association with brain structure. This study is among the first multimodal neuroimaging studies examining the brain structure of children exposed to agricultural pesticides, specifically OC. These findings suggest OC pesticide exposure may disrupt normal brain development in children, highlighting the need for further neuroimaging studies within this vulnerable population.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">11</style></issue></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Thomas A Arcury</style></author><author><style face="normal" font="default" size="100%">Haiying Chen</style></author><author><style face="normal" font="default" size="100%">Sara A Quandt</style></author><author><style face="normal" font="default" size="100%">Jennifer W Talton</style></author><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author><author><style face="normal" font="default" size="100%">Richard P Scott</style></author><author><style face="normal" font="default" size="100%">Phillip Summers</style></author><author><style face="normal" font="default" size="100%">Paul J Laurienti</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Pesticide Exposure among Latinx Children in Rural Farmworker and Urban Non-Farmworker Communities: Associations with Locality and Season.</style></title><secondary-title><style face="normal" font="default" size="100%">Int J Environ Res Public Health</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Int J Environ Res Public Health</style></alt-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Agriculture</style></keyword><keyword><style  face="normal" font="default" size="100%">Child</style></keyword><keyword><style  face="normal" font="default" size="100%">Chlorpyrifos</style></keyword><keyword><style  face="normal" font="default" size="100%">Environmental Exposure</style></keyword><keyword><style  face="normal" font="default" size="100%">Gas Chromatography-Mass Spectrometry</style></keyword><keyword><style  face="normal" font="default" size="100%">Hispanic or Latino</style></keyword><keyword><style  face="normal" font="default" size="100%">Humans</style></keyword><keyword><style  face="normal" font="default" size="100%">Pesticides</style></keyword><keyword><style  face="normal" font="default" size="100%">Pyrethrins</style></keyword><keyword><style  face="normal" font="default" size="100%">Seasons</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2023 Apr 26</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">20</style></volume><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;This study uses repeated measures to document the pesticide exposure of rural and urban Latinx children (age eight at baseline), and to compare these children in terms of the frequency and concentration of their exposure to a large set of pesticides, accounting for season. We used silicone wristbands worn for one week up to ten times at quarterly intervals from 2018 to 2022 to assess pesticide exposure in children from rural farmworker ( = 75) and urban non-farmworker ( = 61) families. We determined the detection and concentrations (ng/g) of 72 pesticides and pesticide degradation products in the wristbands using gas chromatography electron capture detection and gas chromatography mass spectrometry. The most frequently detected pesticide classes were organochlorines, pyrethroids, and organophosphates. Controlling for season, organochlorine or phenylpyrazole detections were less likely for rural children than for urban children. Detections of organochlorines, pyrethroids, or organophosphates were lower in spring and summer versus winter. Controlling for season, urban children had greater concentrations of organochlorines, while rural children had greater concentrations of pyrethroids and Chlorpyrifos. Pesticide concentrations were lower in winter and spring compared with summer and fall. These results further document that pesticides are ubiquitous in the living environment for children in vulnerable, immigrant communities.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">9</style></issue></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>3</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Christopher Husted</style></author><author><style face="normal" font="default" size="100%">Brittney Logan</style></author><author><style face="normal" font="default" size="100%">Kate Megquier</style></author><author><style face="normal" font="default" size="100%">Dane Genereux</style></author><author><style face="normal" font="default" size="100%">Diana Rohlman</style></author><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author><author><style face="normal" font="default" size="100%">Frances Chen</style></author><author><style face="normal" font="default" size="100%">Elinor Karlsson</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Spatial and Cancer-Related Variation in Chemical Exposures Among Domestic Dogs</style></title><secondary-title><style face="normal" font="default" size="100%"> UMASS Retreat, UMASS Cancer Retreat </style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">10/2023</style></date></pub-dates></dates><language><style face="normal" font="default" size="100%">eng</style></language></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Gosline, Sara J C</style></author><author><style face="normal" font="default" size="100%">Kim, Doo Nam</style></author><author><style face="normal" font="default" size="100%">Pande, Paritosh</style></author><author><style face="normal" font="default" size="100%">Thomas, Dennis G</style></author><author><style face="normal" font="default" size="100%">Truong, Lisa</style></author><author><style face="normal" font="default" size="100%">Peter D Hoffman</style></author><author><style face="normal" font="default" size="100%">Michael L Barton</style></author><author><style face="normal" font="default" size="100%">Loftus, Joseph</style></author><author><style face="normal" font="default" size="100%">Moran, Addy</style></author><author><style face="normal" font="default" size="100%">Hampton, Shawn</style></author><author><style face="normal" font="default" size="100%">Dowson, Scott</style></author><author><style face="normal" font="default" size="100%">Franklin, Lyndsey</style></author><author><style face="normal" font="default" size="100%">David J Degnan</style></author><author><style face="normal" font="default" size="100%">Anderson, Lindsey</style></author><author><style face="normal" font="default" size="100%">Thessen, Anne</style></author><author><style face="normal" font="default" size="100%">Robyn L Tanguay</style></author><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author><author><style face="normal" font="default" size="100%">Katrina M Waters</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">The Superfund Research Program Analytics Portal: linking environmental chemical exposure to biological phenotypes.</style></title><secondary-title><style face="normal" font="default" size="100%">Sci Data</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Sci Data</style></alt-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Animals</style></keyword><keyword><style  face="normal" font="default" size="100%">Environmental Exposure</style></keyword><keyword><style  face="normal" font="default" size="100%">Hazardous Substances</style></keyword><keyword><style  face="normal" font="default" size="100%">Humans</style></keyword><keyword><style  face="normal" font="default" size="100%">Northwestern United States</style></keyword><keyword><style  face="normal" font="default" size="100%">Polycyclic Aromatic Hydrocarbons</style></keyword><keyword><style  face="normal" font="default" size="100%">Zebrafish</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2023 Mar 21</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">151</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;The OSU/PNNL Superfund Research Program (SRP) represents a longstanding collaboration to quantify Polycyclic Aromatic Hydrocarbons (PAHs) at various superfund sites in the Pacific Northwest and assess their potential impact on human health. To link the chemical measurements to biological activity, we describe the use of the zebrafish as a high-throughput developmental toxicity model that provides quantitative measurements of the exposure to chemicals. Toward this end, we have linked over 150 PAHs found at Superfund sites to the effect of these same chemicals in zebrafish, creating a rich dataset that links environmental exposure to biological response. To quantify this response, we have implemented a dose-response modelling pipeline to calculate benchmark dose parameters which enable potency comparison across over 500 chemicals and 12 of the phenotypes measured in zebrafish. We provide a rich dataset for download and analysis as well as a web portal that provides public access to this dataset via an interactive web site designed to support exploration and re-use of these data by the scientific community at http://srp.pnnl.gov .&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Dobbins, Dorothy L</style></author><author><style face="normal" font="default" size="100%">Haiying Chen</style></author><author><style face="normal" font="default" size="100%">Milton J. Cepeda</style></author><author><style face="normal" font="default" size="100%">Berenson, Lesley</style></author><author><style face="normal" font="default" size="100%">Jennifer W Talton</style></author><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author><author><style face="normal" font="default" size="100%">Jonathan H Burdette</style></author><author><style face="normal" font="default" size="100%">Sara A Quandt</style></author><author><style face="normal" font="default" size="100%">Thomas A Arcury</style></author><author><style face="normal" font="default" size="100%">Paul J Laurienti</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Comparing impact of pesticide exposure on cognitive abilities of Latinx children from rural farmworker and urban non-farmworker families in North Carolina.</style></title><secondary-title><style face="normal" font="default" size="100%">Neurotoxicol Teratol</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Neurotoxicol Teratol</style></alt-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Agriculture</style></keyword><keyword><style  face="normal" font="default" size="100%">Child</style></keyword><keyword><style  face="normal" font="default" size="100%">Child, Preschool</style></keyword><keyword><style  face="normal" font="default" size="100%">Cognition</style></keyword><keyword><style  face="normal" font="default" size="100%">Environmental Exposure</style></keyword><keyword><style  face="normal" font="default" size="100%">Farmers</style></keyword><keyword><style  face="normal" font="default" size="100%">Female</style></keyword><keyword><style  face="normal" font="default" size="100%">Humans</style></keyword><keyword><style  face="normal" font="default" size="100%">North Carolina</style></keyword><keyword><style  face="normal" font="default" size="100%">Occupational Exposure</style></keyword><keyword><style  face="normal" font="default" size="100%">Pesticides</style></keyword><keyword><style  face="normal" font="default" size="100%">Pregnancy</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2022 Jul-Aug</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">92</style></volume><pages><style face="normal" font="default" size="100%">107106</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;Pesticide exposure remains a health hazard despite extensive study into adverse effects. Children in vulnerable populations, such as Latinx children in farmworker families, are particularly at risk for exposure. Several studies have demonstrated the detrimental cognitive effects of prenatal exposure to pesticides, particularly organophosphates (OPs) within this high-risk group. However, results from studies investigating the cognitive effects of early childhood pesticide exposure are equivocal. Most studies examining the effects of pesticide exposure have used correlative analyses rather than examining populations with expected high and low exposure. The current study compares 8-year-old children from rural families of farmworkers and urban, non-farmworker families. We used the Weschler Intelligence Scale for Children - Fifth Edition (WISC-V) to assess cognitive performance in these children. We designed this study with the expectation that children from farmworker families would have greater exposure to agricultural pesticides than urban, non-farmworker children. This assumption of exposure to agricultural pesticides was confirmed in a recent report that assessed exposure probabilities using life history calendars. However, data from passive wristband sampling of acute (1-week) pesticide exposure from these same children indicate that both study populations have considerable pesticide exposure but to different chemicals. As expected the children of farmworkers had greater OP exposure than non-farmworker children, but the non-farmworker children had greater exposure to two other classes of insecticides (organochlorines [OCs] and pyrethroids). Our analyses considered these findings. A comparison of the cognitive scores between groups revealed that children from farmworker families had slightly higher performance on the Visual-Spatial Index (VSI) and Verbal Comprehension Index (VCI) when compared to children from non-farmworker families. Regression analyses where pesticide exposure was included as covariates revealed that OC exposure accounted for the largest portion of the group differences for both VSI and VCI. However, a post-hoc moderation analysis did not find significant interactions. The main study outcome was that the non-farmworker children exhibited lower WISC-V scores than the children from farmworker families, and the analyses incorporating pesticide exposure measures raise the hypothesis the that pervasive and persistent nature of a variety of pesticides may have adverse effects on the neurodevelopment of young Latinx children whether living in rural or non-farmworker environments.&lt;/p&gt;
</style></abstract></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Megan E Romano</style></author><author><style face="normal" font="default" size="100%">Gallagher, Lisa</style></author><author><style face="normal" font="default" size="100%">Brett T Doherty</style></author><author><style face="normal" font="default" size="100%">Yeum, Dabin</style></author><author><style face="normal" font="default" size="100%">Lee, Sunmi</style></author><author><style face="normal" font="default" size="100%">Takazawa, Mari</style></author><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author><author><style face="normal" font="default" size="100%">Kannan, Kurunthachalam</style></author><author><style face="normal" font="default" size="100%">Margaret R Karagas</style></author></authors><translated-authors><author><style face="normal" font="default" size="100%">program collaborators for Environmental Influences on Child Health Outcomes</style></author></translated-authors></contributors><titles><title><style face="normal" font="default" size="100%">Inter-method reliability of silicone exposome wristbands and urinary biomarker assays in a pregnancy cohort.</style></title><secondary-title><style face="normal" font="default" size="100%">Environ Res</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Environ Res</style></alt-title></titles><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2022 Nov</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">214</style></volume><pages><style face="normal" font="default" size="100%">113981</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;Silicone wristbands act as passive environmental samplers capable of detecting and measuring concentrations of a variety of chemicals. They offer a noninvasive method to collect complex exposure data in large-scale epidemiological studies. We evaluated the inter-method reliability of silicone wristbands and urinary biomarkers in the New Hampshire Birth Cohort Study. A subset of study participants (n&amp;nbsp;=&amp;nbsp;96) provided a urine sample and wore a silicone wristband for 7 days at approximately 12 gestational weeks. Women were instructed to wear the wristbands during all their normal activities. Concentrations of urinary compounds and metabolites in the urine and parent compounds in wristbands were compared. High detection rates were observed for triphenyl phosphate (76.0%) and benzophenone (78.1%) in wristbands, although the distribution of corresponding urinary concentrations of chemicals did not differ according to whether chemicals were detected or not detected in wristbands. While detected among only 8.3% of wristbands, median urinary triclosan concentrations were higher among those with triclosan detected in wristbands (9.04&amp;nbsp;ng/mL) than without (0.16&amp;nbsp;ng/mL). For most chemicals slight to fair agreement was observed across exposure assessment methods, potentially due to low rates of detection in the wristbands for chemicals where observed urinary concentrations were relatively low as compared to background concentrations in the general population. Our findings support the growing body of research in support of deploying silicone wristbands as an important exposure assessment tool.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">Pt 3</style></issue></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Abiodun O Oluyomi</style></author><author><style face="normal" font="default" size="100%">Panthagani, Kristen</style></author><author><style face="normal" font="default" size="100%">Sotelo, Jesus</style></author><author><style face="normal" font="default" size="100%">Gu, Xiangjun</style></author><author><style face="normal" font="default" size="100%">Armstrong, Georgina</style></author><author><style face="normal" font="default" size="100%">Luo, Dan Na</style></author><author><style face="normal" font="default" size="100%">Kristi L Hoffman</style></author><author><style face="normal" font="default" size="100%">Diana Rohlman</style></author><author><style face="normal" font="default" size="100%">Lane G Tidwell</style></author><author><style face="normal" font="default" size="100%">Winnifred Hamilton</style></author><author><style face="normal" font="default" size="100%">Symanski, Elaine</style></author><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author><author><style face="normal" font="default" size="100%">Petrosino, Joseph F</style></author><author><style face="normal" font="default" size="100%">Cheryl Walker</style></author><author><style face="normal" font="default" size="100%">Melissa Bondy</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Houston hurricane Harvey health (Houston-3H) study: assessment of allergic symptoms and stress after hurricane Harvey flooding.</style></title><secondary-title><style face="normal" font="default" size="100%">Environ Health</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Environ Health</style></alt-title></titles><dates><year><style  face="normal" font="default" size="100%">2021</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2021 Jan 19</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">20</style></volume><pages><style face="normal" font="default" size="100%">9</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;BACKGROUND: &lt;/strong&gt;In August 2017, Hurricane Harvey caused unprecedented flooding across the greater Houston area. Given the potential for widespread flood-related exposures, including mold and sewage, and the emotional and mental toll caused by the flooding, we sought to evaluate the short- and long-term impact of flood-related exposures on the health of Houstonians. Our objectives were to assess the association of flood-related exposures with allergic symptoms and stress among Houston-area residents at two time points: within approximately 30 days (T1) and 12 months (T2) after Hurricane Harvey&#039;s landfall.&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;METHODS: &lt;/strong&gt;The Houston Hurricane Harvey Health (Houston-3H) Study enrolled a total of 347 unique participants from four sites across Harris County at two times: within approximately 1-month of Harvey (T1, n&amp;nbsp;= 206) and approximately 12-months after Harvey (T2, n&amp;nbsp;= 266), including 125 individuals who participated at both time points. Using a self-administered questionnaire, participants reported details on demographics, flood-related exposures, and health outcomes, including allergic symptoms and stress.&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;RESULTS: &lt;/strong&gt;The majority of participants reported hurricane-related flooding in their homes at T1 (79.1%) and T2 (87.2%) and experienced at least one allergic symptom after the hurricane (79.4% at T1 and 68.4% at T2). In general, flood-exposed individuals were at increased risk of upper respiratory tract allergic symptoms, reported at both the T1 and T2 time points, with exposures to dirty water and mold associated with increased risk of multiple allergic symptoms. The mean stress score of study participants at T1 was 8.0 ± 2.1 and at T2, 5.1 ± 3.2, on a 0-10 scale. Participants who experienced specific flood-related exposures reported higher stress scores when compared with their counterparts, especially 1 year after Harvey. Also, a supplementary paired-samples analysis showed that reports of wheezing, shortness of breath, and skin rash did not change between T1 and T2, though other conditions were less commonly reported at T2.&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;CONCLUSION: &lt;/strong&gt;These initial Houston-3H findings demonstrate that flooding experiences that occurred as a consequence of Hurricane Harvey had lasting impacts on the health of Houstonians up to 1 year after the hurricane.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Christine C Ghetu</style></author><author><style face="normal" font="default" size="100%">Richard P Scott</style></author><author><style face="normal" font="default" size="100%">Glenn R Wilson</style></author><author><style face="normal" font="default" size="100%">Rachel Liu-May</style></author><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Improvements in identification and quantitation of alkylated PAHs and forensic ratio sourcing.</style></title><secondary-title><style face="normal" font="default" size="100%">Anal Bioanal Chem</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Anal Bioanal Chem</style></alt-title></titles><dates><year><style  face="normal" font="default" size="100%">2021</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2021 Mar</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">413</style></volume><pages><style face="normal" font="default" size="100%">1651-1664</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;Parent and alkylated polycyclic aromatic hydrocarbons (PAHs) are present in a number of different sources in varying proportions depending on the source material and weathering. This range of PAH sources can make it difficult to determine the origin of exposure(s). Ratios of alkylated and parent PAHs have been applied as a forensic tool to distinguish between different sources. However, few studies have examined PAH ratios comprehensively as indicators for sourcing beyond a single study area or matrix type. In this paper, we introduce an expanded analytical method based on ASTM D7363-13a which we adapted for a gas chromatography triple quadrupole mass spectrometry instrument. The modifications increase selectivity and sensitivity compared to the ASTM method. We added five alkylated series to the method. This method has then been applied to 22 independent forensic ratios. We evaluated the method and the forensic ratios with certified reference materials and known environmental samples. This analytical method and thirteen PAH ratios were found to accurately predict sources of PAHs.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Thomas A Arcury</style></author><author><style face="normal" font="default" size="100%">Haiying Chen</style></author><author><style face="normal" font="default" size="100%">Sara A Quandt</style></author><author><style face="normal" font="default" size="100%">Jennifer W Talton</style></author><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author><author><style face="normal" font="default" size="100%">Richard P Scott</style></author><author><style face="normal" font="default" size="100%">Jensen, Anna</style></author><author><style face="normal" font="default" size="100%">Paul J Laurienti</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Pesticide exposure among Latinx children: Comparison of children in rural, farmworker and urban, non-farmworker communities.</style></title><secondary-title><style face="normal" font="default" size="100%">Sci Total Environ</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Sci Total Environ</style></alt-title></titles><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2020 Dec 29</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">763</style></volume><pages><style face="normal" font="default" size="100%">144233</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;Personal pesticide exposure is not well characterized among children in vulnerable, immigrant communities. We used silicone wristbands in 2018-2019 to assess pesticide exposure in 8&amp;nbsp;year old Latinx boys and girls in rural, farmworker families (n&amp;nbsp;=&amp;nbsp;73) and urban, non-farmworker families (n&amp;nbsp;=&amp;nbsp;60) living in North Carolina who were enrolled in the PACE5 Study, a community-based participatory research study. We determined the detection and concentrations (ng/g) of 75 pesticides and pesticide degradation products in the silicone wristbands worn for one week using gas chromatography electron capture detection and employed gas chromatography mass spectrometry. Differences by personal and family characteristics were tested using analysis of variance or Wilcoxon Rank Sum tests when necessary. Pesticide concentrations above the limit of detection were analyzed, and reported as geometric means and 95% confidence intervals (CI). The most frequently detected pesticide classes were organochlorines (85.7%), pyrethroids (65.4%), and organophosphates (59.4%), with the most frequently detected specific pesticides being alpha-chlordane (69.2%), trans-nonachlor (67.7%), gamma-chlordane (66.2%), chlorpyrifos (54.9%), cypermethrin (49.6%), and trans-permethrin (39.1%). More of those children in urban, non-farmworker families had detections of organochlorines (93.3% vs. 79.5, p&amp;nbsp;=&amp;nbsp;0.0228) and pyrethroids (75.0% vs. 57.5%, p&amp;nbsp;=&amp;nbsp;0.0351) than did those in rural, farmworker families; more children in rural, farmworker families had detections for organophosphates (71.2% vs. 45.0%, p=&amp;nbsp;0.0022). Children in urban, non-farmworker families had greater concentrations of alpha-chlordane (geometric mean (GM) 18.98, 95% CI 14.14, 25.47 vs. 10.25, 95% CI 7.49, 14.03; p=&amp;nbsp;0.0055) and dieldrin (GM 17.38, 95% CI 12.78 23.62 vs. 8.10, 95% CI 5.47, 12.00; p=&amp;nbsp;0.0034) than did children in rural, farmworker families. These results support the position that pesticides are ubiquitous in the living environment for children in vulnerable, immigrant communities, and argue for greater effort in documenting the widespread nature of pesticide exposure among children, with greater effort to reduce pesticide exposure.&lt;/p&gt;
</style></abstract></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>13</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Christine C Ghetu</style></author><author><style face="normal" font="default" size="100%">Richard P Scott</style></author><author><style face="normal" font="default" size="100%">Glenn R Wilson</style></author><author><style face="normal" font="default" size="100%">Rachel Liu-May</style></author><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Predicting contaminant sources in environmental samples using GC-MS/MS alkylated PAH analysis and a comprehensive list of forensic ratios</style></title><secondary-title><style face="normal" font="default" size="100%">SETAC North America 41st Annual Meeting, Virtual.</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">11/2020</style></date></pub-dates></dates><language><style face="normal" font="default" size="100%">eng</style></language></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>3</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Christine C Ghetu</style></author><author><style face="normal" font="default" size="100%">Richard P Scott</style></author><author><style face="normal" font="default" size="100%">Glenn R Wilson</style></author><author><style face="normal" font="default" size="100%">Rachel Liu-May</style></author><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Predicting contaminant sources in environmental samples using GC-MS/MS alkylated PAH analysis and a comprehensive list of forensic ratios</style></title><secondary-title><style face="normal" font="default" size="100%">NIEHS Superfund Research Program 2020 Annual Meeting, Virtual</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">12/2020</style></date></pub-dates></dates><language><style face="normal" font="default" size="100%">eng</style></language></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Vermeulen, Roel</style></author><author><style face="normal" font="default" size="100%">Downward, George S</style></author><author><style face="normal" font="default" size="100%">Zhang, Jinming</style></author><author><style face="normal" font="default" size="100%">Hu, Wei</style></author><author><style face="normal" font="default" size="100%">Portengen, Lützen</style></author><author><style face="normal" font="default" size="100%">Bassig, Bryan A</style></author><author><style face="normal" font="default" size="100%">Hammond, S Katharine</style></author><author><style face="normal" font="default" size="100%">Wong, Jason Y Y</style></author><author><style face="normal" font="default" size="100%">Li, Jihua</style></author><author><style face="normal" font="default" size="100%">Reiss, Boris</style></author><author><style face="normal" font="default" size="100%">He, Jun</style></author><author><style face="normal" font="default" size="100%">Tian, Linwei</style></author><author><style face="normal" font="default" size="100%">Yang, Kaiyun</style></author><author><style face="normal" font="default" size="100%">Seow, Wei Jie</style></author><author><style face="normal" font="default" size="100%">Xu, Jun</style></author><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author><author><style face="normal" font="default" size="100%">Ji, Bu-Tian</style></author><author><style face="normal" font="default" size="100%">Silverman, Debra</style></author><author><style face="normal" font="default" size="100%">Chanock, Stephen</style></author><author><style face="normal" font="default" size="100%">Huang, Yunchao</style></author><author><style face="normal" font="default" size="100%">Rothman, Nathaniel</style></author><author><style face="normal" font="default" size="100%">Lan, Qing</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Constituents of Household Air Pollution and Risk of Lung Cancer among Never-Smoking Women in Xuanwei and Fuyuan, China.</style></title><secondary-title><style face="normal" font="default" size="100%">Environ Health Perspect</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Environ. Health Perspect.</style></alt-title></titles><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2019 Sep</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">127</style></volume><pages><style face="normal" font="default" size="100%">97001</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;BACKGROUND: &lt;/strong&gt;Lung cancer rates among never-smoking women in Xuanwei and Fuyuan in China are among the highest in the world and have been attributed to the domestic use of smoky (bituminous) coal for heating and cooking. However, the key components of coal that drive lung cancer risk have not been identified.&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;OBJECTIVES: &lt;/strong&gt;We aimed to investigate the relationship between lifelong exposure to the constituents of smoky coal (and other fuel types) and lung cancer.&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;METHODS: &lt;/strong&gt;Using a population-based case-control study of lung cancer among 1,015 never-smoking female cases and 485 controls, we examined the association between exposure to 43 household air pollutants and lung cancer. Pollutant predictions were derived from a comprehensive exposure assessment study, which included methylated polycyclic aromatic hydrocarbons (PAHs), which have never been directly evaluated in an epidemiological study of any cancer. Hierarchical clustering and penalized regression were applied in order to address high colinearity in exposure variables.&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;RESULTS: &lt;/strong&gt;The strongest association with lung cancer was for a cluster of 25 PAHs [odds ratio (OR): 2.21; 95% confidence interval (CI): 1.67, 2.87 per 1 standard deviation (SD) change], within which 5-methylchrysene (5-MC), a mutagenic and carcinogenic PAH, had the highest individual observed OR (5.42; 95% CI: 0.94, 27.5). A positive association with nitrogen dioxide ([Formula: see text]) was also observed (OR: 2.06; 95% CI: 1.19, 3.49). By contrast, neither benzo(a)pyrene (BaP) nor fine particulate matter with aerodynamic diameter [Formula: see text] ([Formula: see text]) were associated with lung cancer in the multipollutant models.&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;CONCLUSIONS: &lt;/strong&gt;To our knowledge, this is the first study to comprehensively evaluate the association between lung cancer and household air pollution (HAP) constituents estimated over the entire life course. Given the global ubiquity of coal use domestically for indoor cooking and heating and commercially for electric power generation, our study suggests that more extensive monitoring of coal combustion products, including methylated PAHs, may be warranted to more accurately assess health risks and develop prevention strategies from this exposure. https://doi.org/10.1289/EHP4913.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">9</style></issue></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Harley, Kim G</style></author><author><style face="normal" font="default" size="100%">Parra, Kimberly L</style></author><author><style face="normal" font="default" size="100%">Jose Camacho</style></author><author><style face="normal" font="default" size="100%">Asa Bradman</style></author><author><style face="normal" font="default" size="100%">Nolan, James E S</style></author><author><style face="normal" font="default" size="100%">Lessard, Chloe</style></author><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author><author><style face="normal" font="default" size="100%">Carolyn M Poutasse</style></author><author><style face="normal" font="default" size="100%">Richard P Scott</style></author><author><style face="normal" font="default" size="100%">Lazaro, Giselle</style></author><author><style face="normal" font="default" size="100%">Edgar Cardoso</style></author><author><style face="normal" font="default" size="100%">Daisy Gallardo</style></author><author><style face="normal" font="default" size="100%">Gunier, Robert B</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Determinants of pesticide concentrations in silicone wristbands worn by Latina adolescent girls in a California farmworker community: The COSECHA youth participatory action study.</style></title><secondary-title><style face="normal" font="default" size="100%">Sci Total Environ</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Sci. Total Environ.</style></alt-title></titles><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2018 Oct 23</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">652</style></volume><pages><style face="normal" font="default" size="100%">1022-1029</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;Personal exposure to pesticides has not been well characterized, especially among adolescents. We used silicone wristbands to assess pesticide exposure in 14 to 16 year old Latina girls (N = 97) living in the agricultural Salinas Valley, California, USA and enrolled in the COSECHA (CHAMACOS of Salinas Examining Chemicals in Homes and Agriculture) Study, a youth participatory action study in an agricultural region of California. We determined pesticide concentrations (ng/g/day) in silicone wristbands worn for one week using gas chromatography electron capture detection and employed gas chromatography mass spectrometry to determine the presence or absence of over 1500 chemicals. Predictors of pesticide detections and concentrations were identified using logistic regression, Wilcoxon rank sum tests, and Tobit regression models. The most frequently detected pesticides in wristbands were fipronil sulfide (87%), cypermethrin (56%), dichlorodiphenyldichloroethylene (DDE) (56%), dacthal (53%), and trans-permethrin (52%). Living within 100 m of active agricultural fields, having carpeting in the home, and having an exterminator treat the home in the past six months were associated with higher odds of detecting certain pesticides. Permethrin concentrations were lower for participants who cleaned their homes daily (GM: 1.9 vs. 6.8 ng/g/day, p = 0.01). In multivariable regression models, participants with doormats in the entryway of their home had lower concentrations (p &amp;lt; 0.05) of cypermethrin (87%), permethrin (99%), fipronil sulfide (69%) and DDE (75%). The results suggest that both nearby agricultural pesticide use and individual behaviors are associated with pesticide exposures.&lt;/p&gt;
</style></abstract></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Diana Rohlman</style></author><author><style face="normal" font="default" size="100%">Holly Dixon</style></author><author><style face="normal" font="default" size="100%">Laurel D Kincl</style></author><author><style face="normal" font="default" size="100%">Larkin, Andrew</style></author><author><style face="normal" font="default" size="100%">Evoy, Richard</style></author><author><style face="normal" font="default" size="100%">Michael L Barton</style></author><author><style face="normal" font="default" size="100%">Phillips, Aaron</style></author><author><style face="normal" font="default" size="100%">Elena S Peterson</style></author><author><style face="normal" font="default" size="100%">Scaffidi, Christopher</style></author><author><style face="normal" font="default" size="100%">Julie Herbstman</style></author><author><style face="normal" font="default" size="100%">Katrina M Waters</style></author><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Development of an environmental health tool linking chemical exposures, physical location and lung function.</style></title><secondary-title><style face="normal" font="default" size="100%">BMC Public Health</style></secondary-title><alt-title><style face="normal" font="default" size="100%">BMC Public Health</style></alt-title></titles><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2019 Jul 01</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">19</style></volume><pages><style face="normal" font="default" size="100%">854</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;BACKGROUND: &lt;/strong&gt;A challenge in environmental health research is collecting robust data sets to facilitate comparisons between personal chemical exposures, the environment and health outcomes. To address this challenge, the Exposure, Location and lung Function (ELF) tool was designed in collaboration with communities that share environmental health concerns. These concerns centered on respiratory health and ambient air quality. The ELF collects exposure to polycyclic aromatic hydrocarbons (PAHs), given their association with diminished lung function. Here, we describe the ELF as a novel environmental health assessment tool.&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;METHODS: &lt;/strong&gt;The ELF tool collects chemical exposure for 62 PAHs using passive sampling silicone wristbands, geospatial location data and respiratory lung function measures using a paired hand-held spirometer. The ELF was tested by 10 individuals with mild to moderate asthma for 7 days. Participants wore a wristband each day to collect PAH exposure, carried a cell phone, and performed spirometry daily to collect respiratory health measures. Location data was gathered using the geospatial positioning system technology in an Android cell-phone.&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;RESULTS: &lt;/strong&gt;We detected and quantified 31 PAHs across the study population. PAH exposure data showed spatial and temporal sensitivity within and between participants. Location data was used with existing datasets such as the Toxics Release Inventory and the National Oceanic and Atmospheric Administration (NOAA) Hazard Mapping System. Respiratory health outcomes were validated using criteria from the American Thoracic Society with 94% of participant data meeting standards. Finally, the ELF was used with a high degree of compliance (&amp;gt; 90%) by community members.&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;CONCLUSIONS: &lt;/strong&gt;The ELF is a novel environmental health assessment tool that allows for personal data collection spanning chemical exposures, location and lung function measures as well as self-reported information.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>3</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Holly Dixon</style></author><author><style face="normal" font="default" size="100%">Armstrong, Georgina</style></author><author><style face="normal" font="default" size="100%">Michael L Barton</style></author><author><style face="normal" font="default" size="100%">Alan J Bergmann</style></author><author><style face="normal" font="default" size="100%">Melissa Bondy</style></author><author><style face="normal" font="default" size="100%">Mary L Halbleib</style></author><author><style face="normal" font="default" size="100%">Erin N Haynes</style></author><author><style face="normal" font="default" size="100%">Julie Herbstman</style></author><author><style face="normal" font="default" size="100%">Winnifred Hamilton</style></author><author><style face="normal" font="default" size="100%">Peter D Hoffman</style></author><author><style face="normal" font="default" size="100%">Paul C Jepson</style></author><author><style face="normal" font="default" size="100%">Molly Kile</style></author><author><style face="normal" font="default" size="100%">Laurel D Kincl</style></author><author><style face="normal" font="default" size="100%">Paul J Laurienti</style></author><author><style face="normal" font="default" size="100%">Paula E North</style></author><author><style face="normal" font="default" size="100%">LB Paulik</style></author><author><style face="normal" font="default" size="100%">Petrosino, Joe</style></author><author><style face="normal" font="default" size="100%">Points, Gary L</style></author><author><style face="normal" font="default" size="100%">Carolyn M Poutasse</style></author><author><style face="normal" font="default" size="100%">Diana Rohlman</style></author><author><style face="normal" font="default" size="100%">Richard P Scott</style></author><author><style face="normal" font="default" size="100%">Brian W Smith</style></author><author><style face="normal" font="default" size="100%">Lane G Tidwell</style></author><author><style face="normal" font="default" size="100%">Cheryl Walker</style></author><author><style face="normal" font="default" size="100%">Katrina M Waters</style></author><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Discovery of common chemical exposures across three continents using silicone wristbands</style></title><secondary-title><style face="normal" font="default" size="100%">EMT Research Day, Corvallis, OR</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">01/2019</style></date></pub-dates></dates><pub-location><style face="normal" font="default" size="100%">Corvallis, OR</style></pub-location><language><style face="normal" font="default" size="100%">eng</style></language></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Holly Dixon</style></author><author><style face="normal" font="default" size="100%">Armstrong, Georgina</style></author><author><style face="normal" font="default" size="100%">Michael L Barton</style></author><author><style face="normal" font="default" size="100%">Alan J Bergmann</style></author><author><style face="normal" font="default" size="100%">Melissa Bondy</style></author><author><style face="normal" font="default" size="100%">Mary L Halbleib</style></author><author><style face="normal" font="default" size="100%">Winnifred Hamilton</style></author><author><style face="normal" font="default" size="100%">Erin N Haynes</style></author><author><style face="normal" font="default" size="100%">Julie Herbstman</style></author><author><style face="normal" font="default" size="100%">Peter D Hoffman</style></author><author><style face="normal" font="default" size="100%">Paul C Jepson</style></author><author><style face="normal" font="default" size="100%">Molly Kile</style></author><author><style face="normal" font="default" size="100%">Laurel D Kincl</style></author><author><style face="normal" font="default" size="100%">Paul J Laurienti</style></author><author><style face="normal" font="default" size="100%">Paula E North</style></author><author><style face="normal" font="default" size="100%">Paulik, L Blair</style></author><author><style face="normal" font="default" size="100%">Petrosino, Joe</style></author><author><style face="normal" font="default" size="100%">Points, Gary L</style></author><author><style face="normal" font="default" size="100%">Carolyn M Poutasse</style></author><author><style face="normal" font="default" size="100%">Diana Rohlman</style></author><author><style face="normal" font="default" size="100%">Richard P Scott</style></author><author><style face="normal" font="default" size="100%">Brian W Smith</style></author><author><style face="normal" font="default" size="100%">Lane G Tidwell</style></author><author><style face="normal" font="default" size="100%">Cheryl Walker</style></author><author><style face="normal" font="default" size="100%">Katrina M Waters</style></author><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Discovery of common chemical exposures across three continents using silicone wristbands.</style></title><secondary-title><style face="normal" font="default" size="100%">R Soc Open Sci</style></secondary-title><alt-title><style face="normal" font="default" size="100%">R Soc Open Sci</style></alt-title></titles><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">02/2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">6</style></volume><pages><style face="normal" font="default" size="100%">181836</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;To assess differences and trends in personal chemical exposure, volunteers from 14 communities in Africa (Senegal, South Africa), North America (United States (U.S.)) and South America (Peru) wore 262 silicone wristbands. We analysed wristband extracts for 1530 unique chemicals, resulting in 400 860 chemical data points. The number of chemical detections ranged from 4 to 43 per wristband, with 191 different chemicals detected, and 1339 chemicals were not detected in any wristband. No two wristbands had identical chemical detections. We detected 13 potential endocrine disrupting chemicals in over 50% of all wristbands and found 36 chemicals in common between chemicals detected in three geographical wristband groups (Africa, North America and South America). U.S. children (less than or equal to 11 years) had the highest percentage of flame retardant detections compared with all other participants. Wristbands worn in Texas post-Hurricane Harvey had the highest mean number of chemical detections (28) compared with other study locations (10-25). Consumer product-related chemicals and phthalates were a high percentage of chemical detections across all study locations (36-53% and 18-42%, respectively). Chemical exposures varied among individuals; however, many individuals were exposed to similar chemical mixtures. Our exploratory investigation uncovered personal chemical exposure trends that can help prioritize certain mixtures and chemical classes for future studies.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>3</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Carolyn M Poutasse</style></author><author><style face="normal" font="default" size="100%">Thomas A Arcury</style></author><author><style face="normal" font="default" size="100%">Sara A Quandt</style></author><author><style face="normal" font="default" size="100%">Paul J Laurienti</style></author><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Applications of Passive Silicone Wristband Samplers: Childhood Para-Occupational Exposures to Pesticide Mixtures</style></title><secondary-title><style face="normal" font="default" size="100%">3rd Tribal Environmental Health Summit, Corvallis, OR</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">06/2018</style></date></pub-dates></dates><language><style face="normal" font="default" size="100%">eng</style></language></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>3</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Holly Dixon</style></author><author><style face="normal" font="default" size="100%">Alan J Bergmann</style></author><author><style face="normal" font="default" size="100%">Mary L Halbleib</style></author><author><style face="normal" font="default" size="100%">Erin N Haynes</style></author><author><style face="normal" font="default" size="100%">Julie Herbstman</style></author><author><style face="normal" font="default" size="100%">Peter D Hoffman</style></author><author><style face="normal" font="default" size="100%">Paul C Jepson</style></author><author><style face="normal" font="default" size="100%">Molly Kile</style></author><author><style face="normal" font="default" size="100%">Laurel D Kincl</style></author><author><style face="normal" font="default" size="100%">Paul J Laurienti</style></author><author><style face="normal" font="default" size="100%">Paula E North</style></author><author><style face="normal" font="default" size="100%">LB Paulik</style></author><author><style face="normal" font="default" size="100%">Points, Gary L</style></author><author><style face="normal" font="default" size="100%">Carolyn M Poutasse</style></author><author><style face="normal" font="default" size="100%">Diana Rohlman</style></author><author><style face="normal" font="default" size="100%">Richard P Scott</style></author><author><style face="normal" font="default" size="100%">Smith BW</style></author><author><style face="normal" font="default" size="100%">Lane G Tidwell</style></author><author><style face="normal" font="default" size="100%">Katrina M Waters</style></author><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Comparing chemical exposures across diverse communities using silicone wristbands</style></title><secondary-title><style face="normal" font="default" size="100%">3rd Tribal Environmental Health Summit, Corvallis, OR</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">06/2018</style></date></pub-dates></dates><pub-location><style face="normal" font="default" size="100%">Corvallis, Oregon</style></pub-location><language><style face="normal" font="default" size="100%">eng</style></language></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>3</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Holly Dixon</style></author><author><style face="normal" font="default" size="100%">Bergmann AJ</style></author><author><style face="normal" font="default" size="100%">Mary L Halbleib</style></author><author><style face="normal" font="default" size="100%">Erin N Haynes</style></author><author><style face="normal" font="default" size="100%">Julie Herbstman</style></author><author><style face="normal" font="default" size="100%">Peter D Hoffman</style></author><author><style face="normal" font="default" size="100%">Paul C Jepson</style></author><author><style face="normal" font="default" size="100%">Molly Kile</style></author><author><style face="normal" font="default" size="100%">Laurel D Kincl</style></author><author><style face="normal" font="default" size="100%">Paul J Laurienti</style></author><author><style face="normal" font="default" size="100%">Paula E North</style></author><author><style face="normal" font="default" size="100%">LB Paulik</style></author><author><style face="normal" font="default" size="100%">Points, Gary L</style></author><author><style face="normal" font="default" size="100%">Carolyn M Poutasse</style></author><author><style face="normal" font="default" size="100%">Diana Rohlman</style></author><author><style face="normal" font="default" size="100%">Richard P Scott</style></author><author><style face="normal" font="default" size="100%">Brian W Smith</style></author><author><style face="normal" font="default" size="100%">Lane G Tidwell</style></author><author><style face="normal" font="default" size="100%">Katrina M Waters</style></author><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Comparing Chemical Exposures Across Diverse Communities Using Silicone Wristbands</style></title><secondary-title><style face="normal" font="default" size="100%">Total Exposure Health Conference, Bethesda, MD</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">09/2018</style></date></pub-dates></dates><language><style face="normal" font="default" size="100%">eng</style></language></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>13</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Holly Dixon</style></author><author><style face="normal" font="default" size="100%">Armstrong, Georgina</style></author><author><style face="normal" font="default" size="100%">Michael L Barton</style></author><author><style face="normal" font="default" size="100%">Bergmann AJ</style></author><author><style face="normal" font="default" size="100%">Melissa Bondy</style></author><author><style face="normal" font="default" size="100%">Mary L Halbleib</style></author><author><style face="normal" font="default" size="100%">Erin N Haynes</style></author><author><style face="normal" font="default" size="100%">Julie Herbstman</style></author><author><style face="normal" font="default" size="100%">Winnifred Hamilton</style></author><author><style face="normal" font="default" size="100%">Peter D Hoffman</style></author><author><style face="normal" font="default" size="100%">Paul C Jepson</style></author><author><style face="normal" font="default" size="100%">Molly Kile</style></author><author><style face="normal" font="default" size="100%">Laurel D Kincl</style></author><author><style face="normal" font="default" size="100%">Paul J Laurienti</style></author><author><style face="normal" font="default" size="100%">Paula E North</style></author><author><style face="normal" font="default" size="100%">LB Paulik</style></author><author><style face="normal" font="default" size="100%">Petrosino, Joe</style></author><author><style face="normal" font="default" size="100%">Points, Gary L</style></author><author><style face="normal" font="default" size="100%">Carolyn M Poutasse</style></author><author><style face="normal" font="default" size="100%">Diana Rohlman</style></author><author><style face="normal" font="default" size="100%">Richard P Scott</style></author><author><style face="normal" font="default" size="100%">Brian W Smith</style></author><author><style face="normal" font="default" size="100%">Lane G Tidwell</style></author><author><style face="normal" font="default" size="100%">Cheryl Walker</style></author><author><style face="normal" font="default" size="100%">Katrina M Waters</style></author><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Discovery of common chemical exposures across three continents using silicone wristbands</style></title><secondary-title><style face="normal" font="default" size="100%">FSES External Advisory Committee Meeting, Yachats, OR</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">10/2018</style></date></pub-dates></dates><language><style face="normal" font="default" size="100%">eng</style></language></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>3</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Carolyn M Poutasse</style></author><author><style face="normal" font="default" size="100%">Paul J Laurienti</style></author><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Applications of Passive Silicone Wristband Samplers: Agricultural and Non-Agricultural Childhood Pesticide Exposures</style></title><secondary-title><style face="normal" font="default" size="100%">72nd Annual Meeting of the American Chemical Society Northwest Regional Meeting, Corvallis, OR </style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">06/2017</style></date></pub-dates></dates><language><style face="normal" font="default" size="100%">eng</style></language></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>3</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Carolyn M Poutasse</style></author><author><style face="normal" font="default" size="100%">Thomas A Arcury</style></author><author><style face="normal" font="default" size="100%">Sara A Quandt</style></author><author><style face="normal" font="default" size="100%">Paul J Laurienti</style></author><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Applications of Passive Silicone Wristband Samplers: Childhood Para-Occupational Exposures to Pesticide Mixtures</style></title><secondary-title><style face="normal" font="default" size="100%">27th Annual Meeting of the International Society of Exposure Science, Research Triangle Park, NC</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">10/2017</style></date></pub-dates></dates><language><style face="normal" font="default" size="100%">eng</style></language></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>3</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Carolyn M Poutasse</style></author><author><style face="normal" font="default" size="100%">Paul J Laurienti</style></author><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Applications of Silicone Wristbands: Agricultural and Non-Agricultural Childhood Pesticide Exposures</style></title><secondary-title><style face="normal" font="default" size="100%">Oregon State University, Department of Toxicology 8th Annual Research Day, Corvallis, OR</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">01/2017</style></date></pub-dates></dates><language><style face="normal" font="default" size="100%">eng</style></language></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Shannon T Lipscomb</style></author><author><style face="normal" font="default" size="100%">Megan McClelland</style></author><author><style face="normal" font="default" size="100%">MacDonald, Megan</style></author><author><style face="normal" font="default" size="100%">Cardenas, Andres</style></author><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author><author><style face="normal" font="default" size="100%">Molly Kile</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Cross-sectional study of social behaviors in preschool children and exposure to flame retardants.</style></title><secondary-title><style face="normal" font="default" size="100%">Environ Health</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Environ Health</style></alt-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Child, Preschool</style></keyword><keyword><style  face="normal" font="default" size="100%">Environmental Exposure</style></keyword><keyword><style  face="normal" font="default" size="100%">Environmental Pollutants</style></keyword><keyword><style  face="normal" font="default" size="100%">Female</style></keyword><keyword><style  face="normal" font="default" size="100%">Flame Retardants</style></keyword><keyword><style  face="normal" font="default" size="100%">Halogenated Diphenyl Ethers</style></keyword><keyword><style  face="normal" font="default" size="100%">Humans</style></keyword><keyword><style  face="normal" font="default" size="100%">Male</style></keyword><keyword><style  face="normal" font="default" size="100%">Organophosphates</style></keyword><keyword><style  face="normal" font="default" size="100%">Social Behavior</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2017 03 09</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">16</style></volume><pages><style face="normal" font="default" size="100%">23</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;BACKGROUND: &lt;/strong&gt;Children are exposed to flame retardants from the built environment. Brominated diphenyl ethers (BDE) and organophosphate-based flame retardants (OPFRs) are associated with poorer neurocognitive functioning in children. Less is known, however, about the association between these classes of compounds and children&#039;s emotional and social behaviors. The objective of this study was to determine if flame retardant exposure was associated with measurable differences in social behaviors among children ages 3-5&amp;nbsp;years.&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;METHODS: &lt;/strong&gt;We examined teacher-rated social behaviors measured using the Social Skills Improvement Rating Scale (SSIS) and personal exposure to flame retardants in children aged 3-5&amp;nbsp;years who attended preschool (n = 72). Silicone passive samplers worn for 7&amp;nbsp;days were used to assess personal exposure to 41 compounds using gas chromatography-mass spectrophotometer. These concentrations were then summed into total BDE and total OPFR exposure prior to natural log transformation. Separate generalized additive models were used to evaluate the relationship between seven subscales of the SSIS and lnΣBDE or lnΣOPFR adjusting for other age, sex, adverse social experiences, and family context.&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;RESULTS: &lt;/strong&gt;All children were exposed to a mixture of flame retardant compounds. We observed a dose dependent relationship between lnΣOPFR and two subscales where children with higher exposures were rated by their preschool teachers as having less responsible behavior (p = 0.07) and more externalizing behavior problems (p = 0.03). Additionally, children with higher lnΣBDE exposure were rated by teachers as less assertive (p = 0.007).&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;CONCLUSIONS: &lt;/strong&gt;We observed a cross-sectional association between children&#039;s exposure to flame retardant compounds and teacher-rated social behaviors among preschool-aged children. Children with higher flame retardant exposures exhibited poorer social skills in three domains that play an important role in a child&#039;s ability to succeed academically and socially.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>13</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Carolyn M Poutasse</style></author><author><style face="normal" font="default" size="100%">Paul J Laurienti</style></author><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">NORM 2017 Outstanding Poster Award</style></title><secondary-title><style face="normal" font="default" size="100%">72nd Annual Meeting of the ACS Northwest Regional Meeting (NORM): Innovation and Unanticipated Discoveries, Corvallis, OR</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">06/2017</style></date></pub-dates></dates><language><style face="normal" font="default" size="100%">eng</style></language></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Vidi, Pierre-Alexandre</style></author><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author><author><style face="normal" font="default" size="100%">Haiying Chen</style></author><author><style face="normal" font="default" size="100%">Rebecca Anderson</style></author><author><style face="normal" font="default" size="100%">Salvador-Moreno, Naike</style></author><author><style face="normal" font="default" size="100%">Mora, Dana C</style></author><author><style face="normal" font="default" size="100%">Carolyn M Poutasse</style></author><author><style face="normal" font="default" size="100%">Paul J Laurienti</style></author><author><style face="normal" font="default" size="100%">Daniel, Stephanie S</style></author><author><style face="normal" font="default" size="100%">Thomas A Arcury</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Personal samplers of bioavailable pesticides integrated with a hair follicle assay of DNA damage to assess environmental exposures and their associated risks in children.</style></title><secondary-title><style face="normal" font="default" size="100%">Mutat Res</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Mutat. Res.</style></alt-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Biological Availability</style></keyword><keyword><style  face="normal" font="default" size="100%">Child</style></keyword><keyword><style  face="normal" font="default" size="100%">Community-Based Participatory Research</style></keyword><keyword><style  face="normal" font="default" size="100%">DNA Damage</style></keyword><keyword><style  face="normal" font="default" size="100%">DNA Repair</style></keyword><keyword><style  face="normal" font="default" size="100%">Environmental Exposure</style></keyword><keyword><style  face="normal" font="default" size="100%">Hair Follicle</style></keyword><keyword><style  face="normal" font="default" size="100%">Humans</style></keyword><keyword><style  face="normal" font="default" size="100%">North Carolina</style></keyword><keyword><style  face="normal" font="default" size="100%">Pesticides</style></keyword><keyword><style  face="normal" font="default" size="100%">Risk Assessment</style></keyword><keyword><style  face="normal" font="default" size="100%">Specimen Handling</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2017 Oct</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">822</style></volume><pages><style face="normal" font="default" size="100%">27-33</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;Agriculture in the United States employs youth ages ten and older in work environments with high pesticide levels. Younger children in rural areas may also be affected by indirect pesticide exposures. The long-term effects of pesticides on health and development are difficult to assess and poorly understood. Yet, epidemiologic studies suggest associations with cancer as well as cognitive deficits. We report a practical and cost-effective approach to assess environmental pesticide exposures and their biological consequences in children. Our approach combines silicone wristband personal samplers and DNA damage quantification from hair follicles, and was tested as part of a community-based participatory research (CBPR) project involving ten Latino children from farmworker households in North Carolina. Our study documents high acceptance among Latino children and their caregivers of these noninvasive sampling methods. The personal samplers detected organophosphates, organochlorines, and pyrethroids in the majority of the participants (70%, 90%, 80%, respectively). Pesticides were detected in all participant samplers, with an average of 6.2±2.4 detections/participant sampler. DNA damage in epithelial cells from the sheath and bulb of plucked hairs follicles was quantified by immunostaining 53BP1-labled DNA repair foci. This method is sensitive, as shown by dose response analyses to γ radiations where the lowest dose tested (0.1Gy) led to significant increased 53BP1 foci density. Immunolabeling of DNA repair foci has significant advantages over the comet assay in that specific regions of the follicles can be analyzed. In this cohort of child participants, significant association was found between the number of pesticide detections and DNA damage in the papilla region of the hairs. We anticipate that this monitoring approach of bioavailable pesticides and genotoxicity will enhance our knowledge of the biological effects of pesticides to guide education programs and safety policies.&lt;/p&gt;
</style></abstract></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Reams, Margaret</style></author></authors><secondary-authors><author><style face="normal" font="default" size="100%">Harding, Anna</style></author><author><style face="normal" font="default" size="100%">Subra, Wilma</style></author><author><style face="normal" font="default" size="100%">Lam, Nina</style></author><author><style face="normal" font="default" size="100%">Steven G O&#039;Connell</style></author><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author></secondary-authors></contributors><titles><title><style face="normal" font="default" size="100%">Response, Recovery, and Resilience to Oil Spills and Environmental Disasters: Exploration and Use of Novel Approaches to Enhance Community Resilience</style></title><secondary-title><style face="normal" font="default" size="100%">Journal of Environmental Health</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">09/2017</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">80</style></volume><language><style face="normal" font="default" size="100%">eng</style></language><section><style face="normal" font="default" size="100%">8</style></section></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>13</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Carolyn M Poutasse</style></author><author><style face="normal" font="default" size="100%">Paul J Laurienti</style></author><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Youth Para-Occupational Exposures to Pesticide Mixtures</style></title><secondary-title><style face="normal" font="default" size="100%">Food Safety and Environmental Stewardship (FSES) External Advisory Council (EAC), Corvallis, OR</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">06/2017</style></date></pub-dates></dates><language><style face="normal" font="default" size="100%">eng</style></language></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">JG Teeguarden</style></author><author><style face="normal" font="default" size="100%">Tan, Yu-Mei</style></author><author><style face="normal" font="default" size="100%">Edwards, Stephen W</style></author><author><style face="normal" font="default" size="100%">Leonard, Jeremy A</style></author><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author><author><style face="normal" font="default" size="100%">Corley, Richard A</style></author><author><style face="normal" font="default" size="100%">Molly Kile</style></author><author><style face="normal" font="default" size="100%">Staci M Simonich</style></author><author><style face="normal" font="default" size="100%">Stone, David</style></author><author><style face="normal" font="default" size="100%">Robyn L Tanguay</style></author><author><style face="normal" font="default" size="100%">Katrina M Waters</style></author><author><style face="normal" font="default" size="100%">Harper, Stacey L</style></author><author><style face="normal" font="default" size="100%">Williams, David E</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Completing the Link between Exposure Science and Toxicology for Improved Environmental Health Decision Making: The Aggregate Exposure Pathway Framework.</style></title><secondary-title><style face="normal" font="default" size="100%">Environ Sci Technol</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Environ. Sci. Technol.</style></alt-title></titles><dates><year><style  face="normal" font="default" size="100%">2016</style></year><pub-dates><date><style  face="normal" font="default" size="100%">05/2016</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">50</style></volume><pages><style face="normal" font="default" size="100%">4579-86</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;Driven by major scientific advances in analytical methods, biomonitoring, computation, and a newly articulated vision for a greater impact in public health, the field of exposure science is undergoing a rapid transition from a field of observation to a field of prediction. Deployment of an organizational and predictive framework for exposure science analogous to the &quot;systems approaches&quot; used in the biological sciences is a necessary step in this evolution. Here we propose the aggregate exposure pathway (AEP) concept as the natural and complementary companion in the exposure sciences to the adverse outcome pathway (AOP) concept in the toxicological sciences. Aggregate exposure pathways offer an intuitive framework to organize exposure data within individual units of prediction common to the field, setting the stage for exposure forecasting. Looking farther ahead, we envision direct linkages between aggregate exposure pathways and adverse outcome pathways, completing the source to outcome continuum for more meaningful integration of exposure assessment and hazard identification. Together, the two frameworks form and inform a decision-making framework with the flexibility for risk-based, hazard-based, or exposure-based decision making.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">9</style></issue></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">MacDonald, Megan</style></author><author><style face="normal" font="default" size="100%">Shannon T Lipscomb</style></author><author><style face="normal" font="default" size="100%">Megan McClelland</style></author><author><style face="normal" font="default" size="100%">Duncan, Rob</style></author><author><style face="normal" font="default" size="100%">Becker, Derek</style></author><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author><author><style face="normal" font="default" size="100%">Molly Kile</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Relations of Preschoolers&#039; Visual-Motor and Object Manipulation Skills With Executive Function and Social Behavior.</style></title><secondary-title><style face="normal" font="default" size="100%">Res Q Exerc Sport</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Res Q Exerc Sport</style></alt-title></titles><dates><year><style  face="normal" font="default" size="100%">2016</style></year><pub-dates><date><style  face="normal" font="default" size="100%">12/2016</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">87</style></volume><pages><style face="normal" font="default" size="100%">396-407</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;PURPOSE: &lt;/strong&gt;The purpose of this article was to examine specific linkages between early visual-motor integration skills and executive function, as well as between early object manipulation skills and social behaviors in the classroom during the preschool year.&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;METHOD: &lt;/strong&gt;Ninety-two children aged 3 to 5 years old (Mage&amp;nbsp;=&amp;nbsp;4.31 years) were recruited to participate. Comprehensive measures of visual-motor integration skills, object manipulation skills, executive function, and social behaviors were administered in the fall and spring of the preschool year.&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;RESULTS: &lt;/strong&gt;Our findings indicated that children who had better visual-motor integration skills in the fall had better executive function scores (B&amp;nbsp;=&amp;nbsp;0.47 [0.20], p&amp;nbsp;&amp;lt;&amp;nbsp;.05, β&amp;nbsp;=&amp;nbsp;.27) in the spring of the preschool year after controlling for age, gender, Head Start status, and site location, but not after controlling for children&#039;s baseline levels of executive function. In addition, children who demonstrated better object manipulation skills in the fall showed significantly stronger social behavior in their classrooms (as rated by teachers) in the spring, including more self-control (B -&amp;nbsp;0.03 [0.00], p&amp;nbsp;&amp;lt;&amp;nbsp;.05, β&amp;nbsp;=&amp;nbsp;.40), more cooperation (B&amp;nbsp;=&amp;nbsp;0.02 [0.01], p&amp;nbsp;&amp;lt;&amp;nbsp;.05, β&amp;nbsp;=&amp;nbsp;.28), and less externalizing/hyperactivity (B&amp;nbsp;=&amp;nbsp;-&amp;nbsp;0.02 [0.01], p&amp;nbsp;&amp;lt;&amp;nbsp;.05, β&amp;nbsp;=&amp;nbsp;-&amp;nbsp;.28) after controlling for social behavior in the fall and other covariates.&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;CONCLUSION: &lt;/strong&gt;Children&#039;s visual-motor integration and object manipulation skills in the fall have modest to moderate relations with executive function and social behaviors later in the preschool year. These findings have implications for early learning initiatives and school readiness.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Molly Kile</style></author><author><style face="normal" font="default" size="100%">Richard P Scott</style></author><author><style face="normal" font="default" size="100%">Steven G O&#039;Connell</style></author><author><style face="normal" font="default" size="100%">Shannon T Lipscomb</style></author><author><style face="normal" font="default" size="100%">MacDonald, Megan</style></author><author><style face="normal" font="default" size="100%">Megan McClelland</style></author><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Using silicone wristbands to evaluate preschool children&#039;s exposure to flame retardants.</style></title><secondary-title><style face="normal" font="default" size="100%">Environ Res</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Environ. Res.</style></alt-title></titles><dates><year><style  face="normal" font="default" size="100%">2016</style></year><pub-dates><date><style  face="normal" font="default" size="100%">05/2016</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">147</style></volume><pages><style face="normal" font="default" size="100%">365-72</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;Silicone wristbands can be used as passive sampling tools for measuring personal environmental exposure to organic compounds. Due to the lightweight and simple design, the wristband may be a useful technique for measuring children&#039;s exposure. In this study, we tested the stability of flame retardant compounds in silicone wristbands and developed an analytical approach for measuring 41 flame retardants in the silicone wristband in order to evaluate exposure to these compounds in preschool-aged children. To evaluate the robustness of using wristbands to measure flame retardants, we evaluated the stability of 3 polybrominated diphenyl ethers (BDEs), and 2 organophosphate flame retardants (OPFRs) in wristbands over 84 days and did not find any evidence of significant loss over time at either 4 or -20°C (p&amp;gt;0.16). We recruited a cohort of 92 preschool aged children in Oregon to wear the wristband for 7 days in order to characterize children&#039;s acceptance of the technology, and to characterize their exposure to flame retardants. Seventy-seven parents returned the wristbands for analysis of 35 BDEs, 4 OPFRs, and 2 other brominated flame retardants although 5 were excluded from the exposure assessment due to protocol deviations (n=72). A total of 20 compounds were detected above the limit of quantitation, and 11 compounds including 4 OPFRs and 7 BDEs were detected in over 60% of the samples. Children&#039;s gender, age, race, recruitment site, and family context were not significantly associated with returning wristbands or compliance with protocols. Comparisons between flame retardant data and socio-demographic information revealed significant differences in total exposures to both ΣBDEs and ΣOPFRs based on age of house, vacuuming frequency, and family context. These results demonstrate that preschool children in Oregon are exposed to BDEs that are no longer being produced in the United States and to OPFRs that have been used as an alternative to polybrominated compounds. Silicone wristbands were well tolerated by young children and were useful for characterizing personal exposure to flame retardants that were not bound to particulate matter.&lt;/p&gt;
</style></abstract></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>13</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Miller, A</style></author><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author><author><style face="normal" font="default" size="100%">Erin N Haynes</style></author><author><style face="normal" font="default" size="100%">Lefthand-Begay, C</style></author><author><style face="normal" font="default" size="100%">O’Fallon, L</style></author><author><style face="normal" font="default" size="100%">Kwok, R</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Disasters and Emerging Environmental Threats</style></title><secondary-title><style face="normal" font="default" size="100%">25th Annual Meeting of the International Society for Exposure Science. Henderson, Nevada</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2015</style></year><pub-dates><date><style  face="normal" font="default" size="100%">10/2015</style></date></pub-dates></dates><language><style face="normal" font="default" size="100%">eng</style></language></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>3</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author><author><style face="normal" font="default" size="100%">Laurel D Kincl</style></author><author><style face="normal" font="default" size="100%">Richard P Scott</style></author><author><style face="normal" font="default" size="100%">Steven G O&#039;Connell</style></author><author><style face="normal" font="default" size="100%">Carey E Donald</style></author><author><style face="normal" font="default" size="100%">Molly Kile</style></author><author><style face="normal" font="default" size="100%">Shannon T Lipscomb</style></author><author><style face="normal" font="default" size="100%">MacDonald, Megan</style></author><author><style face="normal" font="default" size="100%">Megan McClelland</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Passive wristband sampler technology used to build bridges: Three Pilot Studies</style></title><secondary-title><style face="normal" font="default" size="100%">EHSC National Mtg. Tucson, AZ</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2015</style></year><pub-dates><date><style  face="normal" font="default" size="100%">04/2015</style></date></pub-dates></dates><language><style face="normal" font="default" size="100%">eng</style></language></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>13</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Carolyn M Poutasse</style></author><author><style face="normal" font="default" size="100%">Sun, C</style></author><author><style face="normal" font="default" size="100%">Lohmann, R</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Polyethylene Sampling Rates of Persistent Organic Pollutants</style></title><secondary-title><style face="normal" font="default" size="100%">University of Rhode Island, Graduate School of Oceanography, Narragansett, RI</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2014</style></year><pub-dates><date><style  face="normal" font="default" size="100%">08/2014</style></date></pub-dates></dates><language><style face="normal" font="default" size="100%">eng</style></language></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>13</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Carolyn M Poutasse</style></author><author><style face="normal" font="default" size="100%">Sun, C</style></author><author><style face="normal" font="default" size="100%">Lohmann, R</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Polyethylene Sampling Rates of Persistent Organic Pollutants</style></title><secondary-title><style face="normal" font="default" size="100%">Haverford College, Undergraduate Research Symposium, Haverford, PA</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2014</style></year><pub-dates><date><style  face="normal" font="default" size="100%">09/2014</style></date></pub-dates></dates><language><style face="normal" font="default" size="100%">eng</style></language></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Julie A Layshock</style></author><author><style face="normal" font="default" size="100%">Staci M Simonich</style></author><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Effect of dibenzopyrene measurement on assessing air quality in Beijing air and possible implications for human health.</style></title><secondary-title><style face="normal" font="default" size="100%">J Environ Monit</style></secondary-title><alt-title><style face="normal" font="default" size="100%">J Environ Monit</style></alt-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Air Pollutants</style></keyword><keyword><style  face="normal" font="default" size="100%">China</style></keyword><keyword><style  face="normal" font="default" size="100%">Cities</style></keyword><keyword><style  face="normal" font="default" size="100%">Environmental Exposure</style></keyword><keyword><style  face="normal" font="default" size="100%">Environmental Monitoring</style></keyword><keyword><style  face="normal" font="default" size="100%">Epidemiological Monitoring</style></keyword><keyword><style  face="normal" font="default" size="100%">Humans</style></keyword><keyword><style  face="normal" font="default" size="100%">Lung Neoplasms</style></keyword><keyword><style  face="normal" font="default" size="100%">Particle Size</style></keyword><keyword><style  face="normal" font="default" size="100%">Polycyclic Hydrocarbons, Aromatic</style></keyword><keyword><style  face="normal" font="default" size="100%">Risk</style></keyword><keyword><style  face="normal" font="default" size="100%">Seasons</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2010</style></year><pub-dates><date><style  face="normal" font="default" size="100%">12/2010</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">2290-8</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;Size fractionated particulate matter (PM) was collected in summer and winter from Beijing, China for the characterization of an expanded list of PAHs and evaluation of air pollution metrics. Summertime ΣPAHs on PM was 14.6 ± 29(PM 1.5), 0.88 ± 0.49(PM 1.5-7.2) and 0.29 ± 0.076(PM 7.2) ng m(-3) air while wintertime concentrations were 493 ± 206(PM 1.5), 26.7 ± 14(PM 1.5-7.2) and 5.3 ± 2.5(PM 7.2) ng m(-3) air. Greater than 90% of the carcinogenic PAHs were concentrated on PM(1.5). Dibenzopyrene isomers made up a significant portion (∼30%) of the total carcinogenic PAH load during the winter. To our knowledge, this is the first report of dibenzopyrenes in the Beijing atmosphere and among the few studies that report these highly potent PAHs in ambient particulate matter. Lifetime risk calculations indicated that 1 out of 10,000 to over 6 out of 100 Beijing residents may have an increased risk of lung cancer due to PAH concentration. Over half of the lifetime risk was attributed to Σdibenzopyrenes. The World Health Organization and Chinese daily PM(10) standard was exceeded on each day of the study, however, PAH limits were only exceeded during the winter. The outcomes of the air pollution metrics were highly dependent on the individual PAHs measured and seasonal variation.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">12</style></issue><custom1><style face="normal" font="default" size="100%">http://www.ncbi.nlm.nih.gov/pubmed/20967364?dopt=Abstract</style></custom1></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>13</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Julie A Layshock</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">EPA Star Fellow</style></title><secondary-title><style face="normal" font="default" size="100%">US Environmental Protection Agency</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2010</style></year></dates><language><style face="normal" font="default" size="100%">eng</style></language></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>3</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Saili, Katerine S</style></author><author><style face="normal" font="default" size="100%">Przybyla, Jennifer</style></author><author><style face="normal" font="default" size="100%">LaDu, Jane</style></author><author><style face="normal" font="default" size="100%">Staci M Simonich</style></author><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author><author><style face="normal" font="default" size="100%">Robyn L Tanguay</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Gene Expression Changes Following Embryonic Bisphenol A Exposure: Exploring The Role Of Estrogen Disruption In BPA-Induced Neurobehavioral Toxicity</style></title><secondary-title><style face="normal" font="default" size="100%">SETAC North America 31st Annual Conference</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2010</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2010</style></date></pub-dates></dates><language><style face="normal" font="default" size="100%">eng</style></language></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>13</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Julie A Layshock</style></author><author><style face="normal" font="default" size="100%">Staci M Simonich</style></author><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Ketone and Quinone Substituted PAH Profiles from Remote and Urban Atmospheric Particulate Matter</style></title><secondary-title><style face="normal" font="default" size="100%">SETAC North America 31st Annual Conference</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2010</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2010</style></date></pub-dates></dates><language><style face="normal" font="default" size="100%">eng</style></language></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Julie A Layshock</style></author><author><style face="normal" font="default" size="100%">Glenn R Wilson</style></author><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Ketone and quinone-substituted polycyclic aromatic hydrocarbons in mussel tissue, sediment, urban dust, and diesel particulate matrices.</style></title><secondary-title><style face="normal" font="default" size="100%">Environ Toxicol Chem</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Environ. Toxicol. Chem.</style></alt-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Animals</style></keyword><keyword><style  face="normal" font="default" size="100%">Dust</style></keyword><keyword><style  face="normal" font="default" size="100%">Environmental Monitoring</style></keyword><keyword><style  face="normal" font="default" size="100%">Environmental Pollutants</style></keyword><keyword><style  face="normal" font="default" size="100%">Geologic Sediments</style></keyword><keyword><style  face="normal" font="default" size="100%">Ketones</style></keyword><keyword><style  face="normal" font="default" size="100%">Mytilus edulis</style></keyword><keyword><style  face="normal" font="default" size="100%">Polycyclic Hydrocarbons, Aromatic</style></keyword><keyword><style  face="normal" font="default" size="100%">Quinones</style></keyword><keyword><style  face="normal" font="default" size="100%">Vehicle Emissions</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2010</style></year><pub-dates><date><style  face="normal" font="default" size="100%">11/2010</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">29</style></volume><pages><style face="normal" font="default" size="100%">2450-60</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;Polycyclic aromatic hydrocarbons (PAHs) substituted with a ketone or quinone functionality (OPAHs) may be important environmental contaminants. The OPAHs from environmental samples have demonstrated toxicity and may be more harmful than PAHs. Knowledge gaps concerning the occurrence of OPAHs in the total environment arise from analytical difficulties, as well as limited standards and methodologies. An optimized method was developed to quantify five ketone and four quinone OPAHs from matrices ranging from biological tissue to diesel particulates. Five National Institute of Standards and Technology Standard Reference Materials (SRMs) were analyzed. This is the first report of OPAH quantitation in SRM 2977 (mussel tissue), SRM 1944 (New York/New Jersey, USA waterway sediment), SRM 1975 (diesel extract), and SRM 1650b (diesel particulate matter) and among the few to report concentrations from SRM 1649 (urban dust). Furthermore, this is one of the first reports of OPAHs in biological tissue. Σ₉OPAHs were 374 ± 59 mg/kg (mussel tissue), 5.4 ± 0.5 mg/kg (sediment), 16.9 ± 1.6 mg/kg (urban dust), 33.4 ± 0.4 mg/kg (diesel extract), and 150 ± 43 mg/kg (diesel particulate matter). In all SRMs, the levels of OPAHs were similar to or exceeded levels of PAHs. Of the OPAHs tested, the most frequently occurring in the environmental matrices were 9-fluorenone, 9,10-anthraquinone, benzofluorenone, and 7,12-benz[a]anthracenequinone.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">11</style></issue><custom1><style face="normal" font="default" size="100%">http://www.ncbi.nlm.nih.gov/pubmed/20830751?dopt=Abstract</style></custom1></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Yang, Dongren</style></author><author><style face="normal" font="default" size="100%">Kim, Kyung Ho</style></author><author><style face="normal" font="default" size="100%">Phimister, Andrew</style></author><author><style face="normal" font="default" size="100%">Bachstetter, Adam D</style></author><author><style face="normal" font="default" size="100%">Ward, Thomas R</style></author><author><style face="normal" font="default" size="100%">Stackman, Robert W</style></author><author><style face="normal" font="default" size="100%">Mervis, Ronald F</style></author><author><style face="normal" font="default" size="100%">Wisniewski, Amy B</style></author><author><style face="normal" font="default" size="100%">Klein, Sabra L</style></author><author><style face="normal" font="default" size="100%">Kodavanti, Prasada Rao S</style></author><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author><author><style face="normal" font="default" size="100%">Wayman, Gary</style></author><author><style face="normal" font="default" size="100%">Pessah, Isaac N</style></author><author><style face="normal" font="default" size="100%">Lein, Pamela J</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Developmental exposure to polychlorinated biphenyls interferes with experience-dependent dendritic plasticity and ryanodine receptor expression in weanling rats.</style></title><secondary-title><style face="normal" font="default" size="100%">Environ Health Perspect</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Environ. Health Perspect.</style></alt-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Animals</style></keyword><keyword><style  face="normal" font="default" size="100%">Animals, Newborn</style></keyword><keyword><style  face="normal" font="default" size="100%">Body Weight</style></keyword><keyword><style  face="normal" font="default" size="100%">Chlorodiphenyl (54% Chlorine)</style></keyword><keyword><style  face="normal" font="default" size="100%">Dendrites</style></keyword><keyword><style  face="normal" font="default" size="100%">Female</style></keyword><keyword><style  face="normal" font="default" size="100%">Gene Expression Regulation, Developmental</style></keyword><keyword><style  face="normal" font="default" size="100%">Green Fluorescent Proteins</style></keyword><keyword><style  face="normal" font="default" size="100%">Litter Size</style></keyword><keyword><style  face="normal" font="default" size="100%">Maze Learning</style></keyword><keyword><style  face="normal" font="default" size="100%">Memory</style></keyword><keyword><style  face="normal" font="default" size="100%">Microtubule-Associated Proteins</style></keyword><keyword><style  face="normal" font="default" size="100%">Neuronal Plasticity</style></keyword><keyword><style  face="normal" font="default" size="100%">Pregnancy</style></keyword><keyword><style  face="normal" font="default" size="100%">Prenatal Exposure Delayed Effects</style></keyword><keyword><style  face="normal" font="default" size="100%">Rats</style></keyword><keyword><style  face="normal" font="default" size="100%">Rats, Sprague-Dawley</style></keyword><keyword><style  face="normal" font="default" size="100%">Ryanodine Receptor Calcium Release Channel</style></keyword><keyword><style  face="normal" font="default" size="100%">Sex Ratio</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2009</style></year><pub-dates><date><style  face="normal" font="default" size="100%">03/2009</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">117</style></volume><pages><style face="normal" font="default" size="100%">426-35</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;BACKGROUND: &lt;/strong&gt;Neurodevelopmental disorders are associated with altered patterns of neuronal connectivity. A critical determinant of neuronal connectivity is the dendritic morphology of individual neurons, which is shaped by experience. The identification of environmental exposures that interfere with dendritic growth and plasticity may, therefore, provide insight into environmental risk factors for neurodevelopmental disorders.&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;OBJECTIVE: &lt;/strong&gt;We tested the hypothesis that polychlorinated biphenyls (PCBs) alter dendritic growth and/or plasticity by promoting the activity of ryanodine receptors (RyRs).&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;METHODS AND RESULTS: &lt;/strong&gt;The Morris water maze was used to induce experience-dependent neural plasticity in weanling rats exposed to either vehicle or Aroclor 1254 (A1254) in the maternal diet throughout gestation and lactation. Developmental A1254 exposure promoted dendritic growth in cerebellar Purkinje cells and neocortical pyramidal neurons among untrained animals but attenuated or reversed experience-dependent dendritic growth among maze-trained littermates. These structural changes coincided with subtle deficits in spatial learning and memory, increased [3H]-ryanodine binding sites and RyR expression in the cerebellum of untrained animals, and inhibition of training-induced RyR upregulation. A congener with potent RyR activity, PCB95, but not a congener with negligible RyR activity, PCB66, promoted dendritic growth in primary cortical neuron cultures and this effect was blocked by pharmacologic antagonism of RyR activity.&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;CONCLUSIONS: &lt;/strong&gt;Developmental exposure to PCBs interferes with normal patterns of dendritic growth and plasticity, and these effects may be linked to changes in RyR expression and function. These findings identify PCBs as candidate environmental risk factors for neurodevelopmental disorders, especially in children with heritable deficits in calcium signaling.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><custom1><style face="normal" font="default" size="100%">http://www.ncbi.nlm.nih.gov/pubmed/19337518?dopt=Abstract</style></custom1></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ackerman, Luke K</style></author><author><style face="normal" font="default" size="100%">Schwindt, Adam R</style></author><author><style face="normal" font="default" size="100%">Staci M Simonich</style></author><author><style face="normal" font="default" size="100%">Koch, Dan C</style></author><author><style face="normal" font="default" size="100%">Blett, Tamara F</style></author><author><style face="normal" font="default" size="100%">Schreck, Carl B</style></author><author><style face="normal" font="default" size="100%">Kent, Michael L</style></author><author><style face="normal" font="default" size="100%">Landers, Dixon H</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Atmospherically deposited PBDEs, pesticides, PCBs, and PAHs in western U.S. National Park fish: concentrations and consumption guidelines.</style></title><secondary-title><style face="normal" font="default" size="100%">Environ Sci Technol</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Environ Sci Technol</style></alt-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Animals</style></keyword><keyword><style  face="normal" font="default" size="100%">Atmosphere</style></keyword><keyword><style  face="normal" font="default" size="100%">Ethers</style></keyword><keyword><style  face="normal" font="default" size="100%">Fishes</style></keyword><keyword><style  face="normal" font="default" size="100%">Guidelines as Topic</style></keyword><keyword><style  face="normal" font="default" size="100%">Pesticides</style></keyword><keyword><style  face="normal" font="default" size="100%">Polybrominated Biphenyls</style></keyword><keyword><style  face="normal" font="default" size="100%">Polychlorinated Biphenyls</style></keyword><keyword><style  face="normal" font="default" size="100%">Polycyclic Compounds</style></keyword><keyword><style  face="normal" font="default" size="100%">United States</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2008</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2008 Apr 01</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">42</style></volume><pages><style face="normal" font="default" size="100%">2334-41</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;Concentrations of polybrominated diphenyl ethers (PBDEs), pesticides, polychlorinated biphenyls (PCBs), and polycyclic aromatic hydrocarbons were measured in 136 fish from 14 remote lakes in 8 western U.S. National Parks/Preserves between 2003 and 2005 and compared to human and wildlife contaminant health thresholds. A sensitive (median detection limit--18 pg/g wet weight), efficient (61% recovery at 8 ng/g), reproducible (4.1% relative standard deviation (RSD)), and accurate (7% deviation from standard reference material (SRM)) analytical method was developed and validated for these analyses. Concentrations of PCBs, hexachlorobenzene, hexachlorocyclohexanes, DDTs, and chlordanes in western U.S. fish were comparable to or lower than mountain fish recently collected from Europe, Canada, and Asia. Dieldrin and PBDE concentrations were higher than recent measurements in mountain fish and Pacific Ocean salmon. Concentrations of most contaminants in western U.S. fish were 1-6 orders of magnitude below calculated recreational fishing contaminant health thresholds. However, lake average contaminant concentrations in fish exceeded subsistence fishing cancer thresholds in 8 of 14 lakes and wildlife contaminant health thresholds for piscivorous birds in 1 of 14 lakes. These results indicate that atmospherically deposited organic contaminants can accumulate in high elevation fish, reaching concentrations relevant to human and wildlife health.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">7</style></issue></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">D Sethajintanin</style></author><author><style face="normal" font="default" size="100%">Johnson, Eugene R</style></author><author><style face="normal" font="default" size="100%">Loper, Bobby R</style></author><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Bioaccumulation profiles of chemical contaminants in fish from the lower Willamette River, Portland Harbor, Oregon.</style></title><secondary-title><style face="normal" font="default" size="100%">Arch Environ Contam Toxicol</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Arch. Environ. Contam. Toxicol.</style></alt-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Animals</style></keyword><keyword><style  face="normal" font="default" size="100%">Environmental Monitoring</style></keyword><keyword><style  face="normal" font="default" size="100%">Environmental Pollutants</style></keyword><keyword><style  face="normal" font="default" size="100%">Fishes</style></keyword><keyword><style  face="normal" font="default" size="100%">Hazardous Waste</style></keyword><keyword><style  face="normal" font="default" size="100%">Insecticides</style></keyword><keyword><style  face="normal" font="default" size="100%">Mercury</style></keyword><keyword><style  face="normal" font="default" size="100%">Oregon</style></keyword><keyword><style  face="normal" font="default" size="100%">Polychlorinated Biphenyls</style></keyword><keyword><style  face="normal" font="default" size="100%">Reference Values</style></keyword><keyword><style  face="normal" font="default" size="100%">Tissue Distribution</style></keyword><keyword><style  face="normal" font="default" size="100%">Water Pollutants, Chemical</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2004</style></year><pub-dates><date><style  face="normal" font="default" size="100%">01/2004</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">46</style></volume><pages><style face="normal" font="default" size="100%">114-23</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;Twenty-five PCBs (polychlorinated biphenyls), 15 organochlorine (OC) pesticides, and mercury were determined in fish from the Willamette River in Oregon, including a Portland Harbor superfund site. Fish were collected during the summer of 2000 along a 20-mile stretch of the lower Willamette River. Concentrations of sumPCBs (sum of 25 individually determined PCB congeners) and sumDDTs (sum of p,p&#039;-DDT, p,p&#039;-DDE, and p,p&#039;-DDD) in fish ranged from 14 to 530 and from 18 to 510 ng/g-wet weight, respectively. SumPCBs concentrations at all sites exceeded US EPA fish advisory&#039;s screening values. Hexachlorobiphenyl congener 153 was the most abundant of the PCBs detected and p,p&#039;-DDE was the most abundant OC pesticide detected. Low levels of dieldrin were detected in fish at all sites with the highest concentration at the superfund site (4.6 ng/g-wet weight), while other OC pesticides tested were near or below detection limits (approximately 2 ng/g). In general, organic chemical contaminant concentrations were highest in fish from the superfund site and were lower further upriver. Smallmouth bass had the highest levels of OC compounds of three fish species examined. They also had the largest site-to-site variations whereas black crappie had little variation throughout the study area. Mercury levels in fish ranged from 13 to 520 ng/g. Historical fish residue data are limited from the Portland Harbor superfund site, what data is available is over a decade old, generally consisted of only a few fish (&amp;lt; or = 3) and analyses quantified only a few PCB congeners (&amp;lt; 3).&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><custom1><style face="normal" font="default" size="100%">http://www.ncbi.nlm.nih.gov/pubmed/15025171?dopt=Abstract</style></custom1></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Loper, Bobby R</style></author><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Determination of pyrethrin and pyrethroid pesticides in urine and water matrixes by liquid chromatography with diode array detection.</style></title><secondary-title><style face="normal" font="default" size="100%">J AOAC Int</style></secondary-title><alt-title><style face="normal" font="default" size="100%">J AOAC Int</style></alt-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Calibration</style></keyword><keyword><style  face="normal" font="default" size="100%">Chromatography, Liquid</style></keyword><keyword><style  face="normal" font="default" size="100%">Humans</style></keyword><keyword><style  face="normal" font="default" size="100%">Indicators and Reagents</style></keyword><keyword><style  face="normal" font="default" size="100%">Insecticides</style></keyword><keyword><style  face="normal" font="default" size="100%">Pyrethrins</style></keyword><keyword><style  face="normal" font="default" size="100%">Reference Standards</style></keyword><keyword><style  face="normal" font="default" size="100%">Spectrometry, Mass, Electrospray Ionization</style></keyword><keyword><style  face="normal" font="default" size="100%">Spectrophotometry, Ultraviolet</style></keyword><keyword><style  face="normal" font="default" size="100%">Water</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2003</style></year><pub-dates><date><style  face="normal" font="default" size="100%">11/2003</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">86</style></volume><pages><style face="normal" font="default" size="100%">1236-40</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;The following pyrethrin and pyrethroid pesticides were determined in urine and water matrixes by liquid chromatography with diode array detection (LC-DAD): pyrethrin I, pyrethrin II, tetramethrin, baythroid, bifenthrin, fenvalerate, phenothrin, allethrin, resmethrin, cis-permethrin, and trans-permethrin. In addition, 3-phenoxybenzyl alcohol, a metabolite of various pyrethroids, was also successfully determined by the analytical method. The matrix extraction was simple, inexpensive, and fast, using only sodium chloride and acetonitrile. The acetonitrile extract was filtered and analyzed by LC-DAD. The method detection limits for the pyrethrin pesticides in 5 mL urine were determined to range from 0.002 to 0.04 microg/mL, depending on the individual pyrethrin. Recoveries from spiked tap water ranged from 77 to 96%; recoveries from urine ranged from 80 to 117%. This method is especially well-suited to clinical investigations, in which rapid analysis of forensic samples is often required.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><custom1><style face="normal" font="default" size="100%">http://www.ncbi.nlm.nih.gov/pubmed/14979708?dopt=Abstract</style></custom1></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>3</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">D Sethajintanin</style></author><author><style face="normal" font="default" size="100%">Johnson, Eugene R</style></author><author><style face="normal" font="default" size="100%">Loper, Bobby R</style></author><author><style face="normal" font="default" size="100%">Brian W Smith</style></author><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Bioaccumulation profiles of chemical contaminants from the Willamette River Portland Harbor Superfund Site and Human Health Risks Assessment</style></title><secondary-title><style face="normal" font="default" size="100%">PNW SETAC Regional Mtg, Portland, OR</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2002</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2002</style></date></pub-dates></dates><language><style face="normal" font="default" size="100%">eng</style></language></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>13</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">D Sethajintanin</style></author><author><style face="normal" font="default" size="100%">Johnson, Eugene R</style></author><author><style face="normal" font="default" size="100%">Loper, Bobby R</style></author><author><style face="normal" font="default" size="100%">Brian W Smith</style></author><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Chemical Bioavailability in Eco-systesm: Case Study of Contaminants In Portland Harbor</style></title><secondary-title><style face="normal" font="default" size="100%">PNW SETAC Regional Mtg, Portland, OR</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2002</style></year><pub-dates><date><style  face="normal" font="default" size="100%">05/2002</style></date></pub-dates></dates><language><style face="normal" font="default" size="100%">eng</style></language></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Loper, Bobby R</style></author><author><style face="normal" font="default" size="100%">Cobb, William T</style></author><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Chemical marker for ALS-inhibitor herbicides: 2-aminobutyric acid proportional in sub-lethal applications.</style></title><secondary-title><style face="normal" font="default" size="100%">J Agric Food Chem</style></secondary-title><alt-title><style face="normal" font="default" size="100%">J. Agric. Food Chem.</style></alt-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Acetolactate Synthase</style></keyword><keyword><style  face="normal" font="default" size="100%">Aminobutyric Acids</style></keyword><keyword><style  face="normal" font="default" size="100%">Autoanalysis</style></keyword><keyword><style  face="normal" font="default" size="100%">Chromatography, Liquid</style></keyword><keyword><style  face="normal" font="default" size="100%">Enzyme Inhibitors</style></keyword><keyword><style  face="normal" font="default" size="100%">Herbicides</style></keyword><keyword><style  face="normal" font="default" size="100%">Kinetics</style></keyword><keyword><style  face="normal" font="default" size="100%">o-Phthalaldehyde</style></keyword><keyword><style  face="normal" font="default" size="100%">Solanum tuberosum</style></keyword><keyword><style  face="normal" font="default" size="100%">Trichloroacetic Acid</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2002</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2002 Apr 24</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">50</style></volume><pages><style face="normal" font="default" size="100%">2601-6</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;A chemical profiling technique for sub-lethal acetolactate synthase (ALS)-inhibitor herbicides (e.g., sulfonylureas, imidazolines, triazolopyrimidine sulfonanilides, and pyrimidyloxy salicylic) was developed using 2-aminobutyric acid, and was found to be directly proportional to application rates in field studies on two varieties of potato plants. An uncomplicated, benign-by-design analytical method for the determination of 2-aminobutyric acid in plant tissue was developed. The method is simple, fast, and automated, entailing a water-trichloroacetic acid extraction followed by precolumn on-line derivatization using o-phthalaldehyde (OPA) solution and liquid chromatographic analyses. Use of reagents and chlorinated organic solvents, and generation of waste, are minimized as compared to other ALS-inhibitor herbicide analytical techniques. Recoveries for a series of fortified plant tissues ranged from 82 to 103%. Two 20-day field trials on two potato varieties, Russet Burbank and Shepody, were conducted during the 2000 and 2001 growing seasons. The study demonstrated that the 2-aminobutyric acid method is an excellent, selective chemical marker technique for ALS-inhibitor herbicides for real world plant matrixes.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">9</style></issue><custom1><style face="normal" font="default" size="100%">http://www.ncbi.nlm.nih.gov/pubmed/11958629?dopt=Abstract</style></custom1></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>3</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author><author><style face="normal" font="default" size="100%">D Sethajintanin</style></author><author><style face="normal" font="default" size="100%">Johnson, Eugene R</style></author><author><style face="normal" font="default" size="100%">Loper, Bobby R</style></author><author><style face="normal" font="default" size="100%">Brian W Smith</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Human Health Risks Associated with Organochlorine Pesticides and PCBs in Fish from the Willamette River &amp; Portland Harbor</style></title><secondary-title><style face="normal" font="default" size="100%">PITTCON®‘01 Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy, New Orleans, LA</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2002</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2002</style></date></pub-dates></dates><language><style face="normal" font="default" size="100%">eng</style></language></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author><author><style face="normal" font="default" size="100%">Cobb, William T</style></author><author><style face="normal" font="default" size="100%">Loper, Bobby R</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Analytical Method for Determination of Shikimic Acid: Shikimic Acid Proportional to Glyphosate Application Rates</style></title><secondary-title><style face="normal" font="default" size="100%">Communications in Soil Science and Plant Analysis </style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2001</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2001</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">32</style></volume><language><style face="normal" font="default" size="100%">eng</style></language><issue><style face="normal" font="default" size="100%">17,18</style></issue><section><style face="normal" font="default" size="100%">2831-2840</style></section></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>3</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">D Sethajintanin</style></author><author><style face="normal" font="default" size="100%">Johnson, Eugene R</style></author><author><style face="normal" font="default" size="100%">Loper, Bobby R</style></author><author><style face="normal" font="default" size="100%">Brian W Smith</style></author><author><style face="normal" font="default" size="100%">Kim A Anderson</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Human Health Risks Associated from PCBs in Fish from the Willamette River &amp; 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M.</style></author><author><style face="normal" font="default" size="100%">Glenn R Wilson</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Experiences with EPA’s Proposed Screening Analyses for Bioconcentratable Compounds</style></title><secondary-title><style face="normal" font="default" size="100%">Environmental Toxicology and Risk Assessment: Seventh Volume</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">1998</style></year><pub-dates><date><style  face="normal" font="default" size="100%">1998</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">7</style></volume><language><style face="normal" font="default" size="100%">eng</style></language></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>27</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Cook, D</style></author><author><style face="normal" font="default" size="100%">LaFleur, L. L.</style></author><author><style face="normal" font="default" size="100%">Parrish, A</style></author><author><style face="normal" font="default" size="100%">Jones, J</style></author><author><style face="normal" font="default" size="100%">Glenn R Wilson</style></author><author><style face="normal" font="default" size="100%">Hoy, D</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Development of a Stable Pulp and Paper Industry Wastewater Reference Material for use in Compliance Monitoring QA/QC Programs</style></title><secondary-title><style face="normal" font="default" size="100%">NCASI</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">1996</style></year></dates><language><style face="normal" font="default" size="100%">eng</style></language></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>27</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">LaFleur, L. L.</style></author><author><style face="normal" font="default" size="100%">Dodo, G</style></author><author><style face="normal" font="default" size="100%">Bousquet, T</style></author><author><style face="normal" font="default" size="100%">Glenn R Wilson</style></author><author><style face="normal" font="default" size="100%">Ikoma, J</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Results of NCASI Analyses of Champion Internation, Cantonment Samples for Selected Chlorinated Phenolics, Total Organic Halogen and PCDD/PCDF</style></title><secondary-title><style face="normal" font="default" size="100%">NCASI</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">1989</style></year></dates><language><style face="normal" font="default" size="100%">eng</style></language></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Tinsley, I J</style></author><author><style face="normal" font="default" size="100%">Lowry, R R</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Fatty acid composition of liver lipids in rats fed brominated fatty acids.</style></title><secondary-title><style face="normal" font="default" size="100%">Lipids</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Lipids</style></alt-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Bromine</style></keyword><keyword><style  face="normal" font="default" size="100%">Dietary Fats</style></keyword><keyword><style  face="normal" font="default" size="100%">Fatty Acids</style></keyword><keyword><style  face="normal" font="default" size="100%">Lipid Metabolism</style></keyword><keyword><style  face="normal" font="default" size="100%">Liver</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">1983</style></year><pub-dates><date><style  face="normal" font="default" size="100%">1983 Sep</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">18</style></volume><pages><style face="normal" font="default" size="100%">661-3</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;Feeding rats diets containing brominated corn oil or di- or tetrabromostearate as the monoglyceride produced changes in fatty acid composition of liver lipids. Those changes associated with the feeding of brominated corn oil or tetrabromostearate could be explained by the accumulation of triglyceride, and the changes associated with the feeding of dibromostearate could result from the proliferation of a membrane system. A unique response to the feeding of diets containing brominated corn oil is an increase in the level of gamma-linolenic acid.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">9</style></issue></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Jones, B A</style></author><author><style face="normal" font="default" size="100%">Tinsley, I J</style></author><author><style face="normal" font="default" size="100%">Lowry, R R</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Toxicology of brominated fatty acids: metabolite concentration and heart and liver changes.</style></title><secondary-title><style face="normal" font="default" size="100%">Lipids</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Lipids</style></alt-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Adipose Tissue</style></keyword><keyword><style  face="normal" font="default" size="100%">Animals</style></keyword><keyword><style  face="normal" font="default" size="100%">Bromine</style></keyword><keyword><style  face="normal" font="default" size="100%">Dietary Fats</style></keyword><keyword><style  face="normal" font="default" size="100%">Fatty Acids</style></keyword><keyword><style  face="normal" font="default" size="100%">Heart</style></keyword><keyword><style  face="normal" font="default" size="100%">Liver</style></keyword><keyword><style  face="normal" font="default" size="100%">Male</style></keyword><keyword><style  face="normal" font="default" size="100%">Myocardium</style></keyword><keyword><style  face="normal" font="default" size="100%">Rats</style></keyword><keyword><style  face="normal" font="default" size="100%">Rats, Inbred Strains</style></keyword><keyword><style  face="normal" font="default" size="100%">Tissue Distribution</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">1983</style></year><pub-dates><date><style  face="normal" font="default" size="100%">1983 Apr</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">18</style></volume><pages><style face="normal" font="default" size="100%">327-34</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;Rats were fed for 35 days diets containing 2% of either brominated corn oil (BCO), monoglyceride of dibromostearate (DBS), monoglyceride of tetrabromostearate (TBS) or a mixture of the two monoglycerides (BMG) which provided proportions of brominated acids comparable to that of the BCO. Hearts from all animals fed BCO were yellow colored and firm in texture. Myocardial cellular degeneration, mild to moderate edema and occasional small necrotic foci were observed. Hearts from animals fed DBS showed moderate edema and some slight necrosis. All diets produced an increase in lipid content of heart. Animals fed the experimental diets developed enlarged livers and showed elevated liver lipid content. The tetrabromostearate appeared to be the more active in producing these changes, in particular a severe intracellular fatty degeneration. Shorter-chain (C-16, C-14) metabolites of di- and tetrabromostearate were identified and the concentration of brominated fatty acids in heart, liver and adipose tissue determined and found to account for 80% of the bromine detected in these tissues by neutron activation analysis. TBS accumulated in liver while the highest concentration of DBS was observed in heart lipids. Although the concentrations of brominated acids in heart and liver lipids were comparable in rats fed BCO or BMG, BCO produced the more pronounced effects. This differential could be due to additional active components in BCO or to a variation in response associated with changes in the location of the fatty acid on the glycerol molecule.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Tinsley, I J</style></author><author><style face="normal" font="default" size="100%">Lowry, R R</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Tissue fatty acid changes and tumor incidence in C3H mice ingesting cottonseed oil.</style></title><secondary-title><style face="normal" font="default" size="100%">Lipids</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Lipids</style></alt-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Animals</style></keyword><keyword><style  face="normal" font="default" size="100%">Cottonseed Oil</style></keyword><keyword><style  face="normal" font="default" size="100%">Fatty Acids</style></keyword><keyword><style  face="normal" font="default" size="100%">Female</style></keyword><keyword><style  face="normal" font="default" size="100%">Mammary Glands, Animal</style></keyword><keyword><style  face="normal" font="default" size="100%">Mammary Neoplasms, Experimental</style></keyword><keyword><style  face="normal" font="default" size="100%">Mice</style></keyword><keyword><style  face="normal" font="default" size="100%">Mice, Inbred C3H</style></keyword><keyword><style  face="normal" font="default" size="100%">Triglycerides</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">1982</style></year><pub-dates><date><style  face="normal" font="default" size="100%">1982 Feb</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">17</style></volume><pages><style face="normal" font="default" size="100%">115-7</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;The incidence of spontaneous mammary tumors in C3H mice at 35 wk was higher in mice fed rations containing cottonseed oil than in mice fed fats of comparable fatty acid composition. The time to 50% (T50) incidence was also shorter in the first group. The fatty acid composition of tissue lipids from mice fed the cottonseed oil showed changes indicating the presence of cyclopropene fatty acids-higher levels of saturates and lower oleate/stearate and palmitoleate/palmitate ratios. A possible association between the development of a spontaneous mammary tumor in the C3H mouse and the presence of cyclopropene fatty acids in the cottonseed oil is indicated.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue></record></records></xml>