Email: 
peter.hoffman@oregonstate.edu
Phone: 
541-737-1776
Education: 

BS Biology, Oregon State University, 1986
BS Microbiology, Oregon State University, 1986

Experience: 

Jun 2016 - Current, Assistant Director, Food Safety and Environmental Stewardship program, Director Dr. Kim A Anderson, Environmental and Molecular Toxicology, Oregon State University.
Jan 2014 - Jun 2016. Senior Faculty Research Assistant. Food Safety and Environmental Stewardship program, Director Dr. Kim A Anderson, Environmental and Molecular Toxicology, Oregon State University
UV-induced degradation of complex Polycylic Aromatic Hydrocarbon (PAH) mixtures under accurately emulated terrestrial conditions.

May 2013 – May 2014 (0.6FTE) Senior Faculty Research Assistant. Laboratory of Dr. Douglas Barofsky, Department of Chemistry/Environmental and Molecular Toxicology, Oregon State University
Responsible for defining the analytical capability of a novel radio frequency-free electromagnetostatic (EMS) cell devised for electron-capture dissociation (ECD) of ions in a electrospray ionization (ESI) hybrid quadrupole/time-of-flight (QTOF) mass spectrometer.

October 2013 – December 2013 (0.4 FTE) Senior Faculty Research Assistant. Laboratory of Dr. Andrew Buermeyer, Department of Environmental and Molecular Toxicology, Oregon State University.
Mismatch repair responses to poly-aromatic hydrocarbon (PAH) treatment of human cell lines. Continuation of an ongoing project defining the spectrum of mutations generated in the human hypoxanthine-guanine phosphoribosyltransferase (HPRT) gene by exposure of mismatch-repair (MMR) proficient and deficient cell lines to PAH/DNA lesion inducing compounds.

1996 – May 2013 Senior Faculty Research Assistant
1990 – 1996 Faculty Research Assistant;
Laboratory of Dr. John Hays, Department of Environmental and Molecular Toxicology, Oregon State University.
Responsible for the management of an active research lab at OSU with a primary focus on DNA repair and genomic stability in a variety of model systems including Arabidopsis thaliana, E. coli, yeast, and cultured human cells.


Book Chapters

Blaustein, AR, Belden, L, Hatch, A, Kats, L, Hoffman, PD, Hays, JB, Marco, A, Chivers, D, Kiesecker, JM,Ultraviolet radiation and amphibians, 2001, Ecosystems, Evolution, and Ultraviolet Radiation

Conference Proceedingss

Hays, JB, Blaustein, AR, Kiesecker, JM, Hoffman, PD, Pandelova, I,Responses of amphibians to solar and artificial UV light: photorepair, survival, and developmental effects, 1996, Proceedings International Congress of Photobiology, Vienna, Austria

Journal Articles

Donald, CE, Elie, MR, Smith, BW, Hoffman, PD, Anderson, KA,Transport stability of pesticides and PAHs sequestered in polyethylene passive sampling devices., 2016, Environ Sci Pollut Res Int

Voinov, VG, Hoffman, PD, Bennett, SE, Beckman, JS, Barofsky, DF,Electron Capture Dissociation of Sodium-Adducted Peptides on a Modified Quadrupole/Time-of-Flight Mass Spectrometer., J. Am. Soc. Mass Spectrom. 2015, 26(12), 2096-104

Anderson, KA, Szelewski, MJ, Wilson, GR, Quimby, BD, Hoffman, PD,Modified ion source triple quadrupole mass spectrometer gas chromatograph for polycyclic aromatic hydrocarbon analyses., J Chromatogr A 2015, 1419(), 89-98

Thurman, LL, Garcia, TS, Hoffman, PD,Elevational differences in trait response to UV-B radiation by long-toed salamander populations., Oecologia 2014, 175(3), 835-45

Bollmann, SR, Tominey, CM, Hoffman, PD, Hoffman, TM C, Hays, JB,Reversion-reporter transgenes to analyze all six base-substitution pathways in Arabidopsis., Plant Physiol. 2011, 155(3), 1286-300

Curtis, MJ, Belcram, K, Bollmann, SR, Tominey, CM, Hoffman, PD, Mercier, R, Hays, JB,Reciprocal chromosome translocation associated with TDNA-insertion mutation in Arabidopsis: genetic and cytological analyses of consequences for gametophyte development and for construction of doubly mutant lines., Planta 2009, 229(4), 731-45

Hoffman, PD, Curtis, MJ, Iwai, S, Hays, JB,Biochemical evolution of DNA polymerase eta: properties of plant, human, and yeast proteins., Biochemistry 2008, 47(16), 4583-96

Wang, H, Hoffman, PD, Lawrence, C, Hays, JB,Testing excision models for responses of mismatch-repair systems to UV photoproducts in DNA., Environ. Mol. Mutagen. 2006, 47(4), 296-306

Hoffman, PD, Wang, H, Lawrence, CW, Iwai, S, Hanaoka, F, Hays, JB,Binding of MutS mismatch repair protein to DNA containing UV photoproducts, "mismatched" opposite Watson--Crick and novel nucleotides, in different DNA sequence contexts., DNA Repair (Amst.) 2005, 4(9), 983-93

Hays, JB, Hoffman, PD, Wang, H,Discrimination and versatility in mismatch repair., DNA Repair (Amst.) 2005, 4(12), 1463-74

Garca-Ortiz, MVictoria, Ariza, RR, Hoffman, PD, Hays, JB, Roldn-Arjona, T,Arabidopsis thaliana AtPOLK encodes a DinB-like DNA polymerase that extends mispaired primer termini and is highly expressed in a variety of tissues., Plant J. 2004, 39(1), 84-97

Hoffman, PD, Leonard, JM, Lindberg, GE, Bollmann, SR, Hays, JB,Rapid accumulation of mutations during seed-to-seed propagation of mismatch-repair-defective Arabidopsis., Genes Dev. 2004, 18(21), 2676-85

Blaustein, AR, Hays, JB, Hoffman, PD, Chivers, D, Kiesecker, JM, WP, L, Marco, A, Reaser, J, Anthony, R,DNA repair and resistance to UV-B radiation in western spotted frogs, 1999, (9:3:1100-1105),

Hays, JB, Hoffman, PD,Measurement of activities of cyclobutane-pyrimidine-dimer and (6-4)-photoproduct photolyases., Methods Mol. Biol. 1999, 113(), 133-46

van de Mortel, T, Buttemer, W, Hoffman, PD, Hays, J, Blaustein, A,A comparison of photolyase activity in three Australian tree frogs., Oecologia 1998, 115(3), 366-369

Landry, LG, Stapleton, AE, Lim, J, Hoffman, PD, Hays, JB, Walbot, V, Last, RL,An Arabidopsis photolyase mutant is hypersensitive to ultraviolet-B radiation., Proc. Natl. Acad. Sci. U.S.A. 1997, 94(1), 328-32

Blaustein, AR, Kiesecker, JM, Hoffman, PD, Hays, JB,The significance of Ultraviolet-B radiation to amphibian population declines. Reviews in Toxicology, 1997, 147-165(),

Hays, JB, Blaustein, AR, Kiesecker, JM, Hoffman, PD, Pandelova, I, Coyle, D, Richardson, T,Developmental responses of amphibians to solar and artificial UVB sources: a comparative study., Photochem. Photobiol. 1996, 64(3), 449-56

Blaustein, AR, Hoffman, PD, Kiesecker, JM, Hays, JB,DNA repair activity and resistance to solar UV-B radiation in eggs of the red-legged frog: Implications for population declines, 1996, (10:1398-1402.),

Hoffman, PD, Batschauer, A, Hays, JB,PHH1, a novel gene from Arabidopsis thaliana that encodes a protein similar to plant blue-light photoreceptors and microbial photolyases., Mol. Gen. Genet. 1996, 253(1-2), 259-65

Hays, J, Hoffman, PD, Blaustein, AR,Differences in DNA-repair activity and sensitivity to UV-B light among eggs and oocytes of declining and stable amphibian species, 1995, (296),

Blaustein, AR, Hoffman, PD, Hokit, DG, Kiesecker, JM, Walls, SC, Hays, JB,UV repair and resistance to solar UV-B in amphibian eggs: a link to population declines?, Proc. Natl. Acad. Sci. U.S.A. 1994, 91(5), 1791-5

Platform/Presentations

Hoffman, PD, Tidwell, LG, Anderson, KA,Toxicity in zebrafish of complex polycyclic aromatic hydrocarbon mixtures exposed to terrestrially-appropriate UV-radiation., 2016, Society for Environmental Toxicology and Chemistry 2016 Annual Meeting, Orlando, Florida, USA

Posters

Hoffman, PD, Anderson, KA,UV-induced degradation of complex polycylic aromatic hydrocarbon mixtures under accurately emulated terrestrial conditions., 2015, SETAC North America 36th Annual Meeting. Salt Lake City, Utah