%0 Generic %D 2022 %T A Novel Framework to Form Sufficiently Similar Mixtures %A Briana N Rivera %A Christine C Ghetu %A Yvonne Chang %A Kim A Anderson %A Susan C Tilton %B Risk Assessment and Mixtures Specialty Section Webinar %8 01/22 %G eng %0 Generic %D 2021 %T Current Approaches to Characterizing Chemical Mixtures %A Briana N Rivera %A Diana Rohlman %A Kim A Anderson %A Susan C Tilton %B Northwest Toxics Community Coalition %8 4/2021 %G eng %0 Generic %D 2021 %T Eric A. Andreasen Travel Award for Excellence in Research and Scholarship %A Briana N Rivera %8 03/2021 %G eng %0 Generic %D 2021 %T Eric A. Andreasen Travel Award for Excellence in Research and Scholarship %A Briana N Rivera %8 03/2021 %G eng %0 Audiovisual Material %D 2021 %T Influences of Household Behavior and Demographics on Indoor Air Quality %A Briana N Rivera %A Christine C Ghetu %A Diana Rohlman %A Kaley A Adams %A Kim A Anderson %B Society of Environmental Toxicology and Chemistry %8 11/2021 %G eng %0 Audiovisual Material %D 2021 %T A Novel Approach to Forming Sufficiently Similar Mixtures from Environmental Exposure Data %A Briana N Rivera %A Christine C Ghetu %A Kim A Anderson %A Susan C Tilton %B Society of Toxicology %8 03/2021 %G eng %0 Generic %D 2021 %T Society of Toxicology Mixtures Specialty Section Best Abstract %A Briana N Rivera %8 03/2021 %G eng %0 Generic %D 2021 %T Society of Toxicology Perry J. Gehring Risk Assessment Award %A Briana N Rivera %8 03/2021 %G eng %0 Generic %D 2020 %T A Comparative Approach to Evaluating Bioactivity of Representative Mixtures %A Briana N Rivera %A Christine C Ghetu %A Kim A Anderson %A Susan C Tilton %B Protecting Our Water Future for Human and Environmental Health %8 01/2020 %G eng %0 Generic %D 2020 %T A Comparative Approach to Evaluating Bioactivity of Representative Mixtures %A Briana N Rivera %A Christine C Ghetu %A Kim A Anderson %A Susan C Tilton %B Protecting Our Water Future for Human and Environmental Health %8 01/2020 %G eng %0 Audiovisual Material %D 2020 %T A Comprehensive Comparison of Indoor vs Outdoor Air Quality Across the United States %A Briana N Rivera %A Christine C Ghetu %A Diana Rohlman %A Kaley A Adams %A Kim A Anderson %B International Society of Exposure Science %8 09/2020 %G eng %0 Generic %D 2020 %T A Comprehensive Comparison of Indoor vs Outdoor Air Quality Across the United States %A Briana N Rivera %A Christine C Ghetu %A Diana Rohlman %A Kaley A Adams %A Kim A Anderson %B Society of Environmental Toxicology and Chemistry %8 11/2020 %G eng %0 Journal Article %J Sci Total Environ %D 2020 %T Environmental surveillance and adverse neonatal health outcomes in foals born near unconventional natural gas development activity. %A Kathleen Mullen %A Briana N Rivera %A Lane G Tidwell %A Renata Ivanek %A Kim A Anderson %A Dorothy Ainsworth %K Animals %K Animals, Newborn %K Environmental Monitoring %K Female %K Horses %K Humans %K Infant, Newborn %K Male %K Natural Gas %K New York %K Outcome Assessment, Health Care %K Pennsylvania %K Pregnancy %X

Studies of neonatal health risks of unconventional natural gas development (UNGD) have not included comprehensive assessments of environmental chemical exposures. We investigated a clustering of dysphagic cases in neonatal foals born between 2014 and 2016 in an area of active UNGD in Pennsylvania (PA),USA. We evaluated equine biological data and environmental exposures on the affected PA farm and an unaffected New York (NY) farm owned by the same proprietor. Dams either spent their entire gestation on one farm or moved to the other farm in late gestation. Over the 21-month study period, physical examinations and blood/tissue samples were obtained from mares and foals on each farm. Grab samples of water, pasture soil and feed were collected; continuous passive sampling of air and water for polycyclic aromatic hydrocarbons was performed. Dysphagia was evaluated as a binary variable; logistic regression was used to identify risk factors. Sixty-five foals were born, 17 (all from PA farm) were dysphagic. Odds of dysphagia increased with the dam residing on the PA farm for each additional month of gestation (OR = 1.4, 95% CI 1.2, 1.7, p = 6.0E-04). Males were more likely to be born dysphagic (OR = 5.5, 95% CI 1.2, 24.5, p = 0.03) than females. Prior to installation of a water filtration/treatment system, PA water concentrations of 3,6-dimethylphenanthrene (p = 6.0E-03), fluoranthene (p = 0.03), pyrene (p = 0.02) and triphenylene (p = 0.01) exceeded those in NY water. Compared to NY farm water, no concentrations of PAHs were higher in PA following installation of the water filtration/treatment system. We provide evidence of an uncommon adverse health outcome (dysphagia) in foals born near UNGD that was eliminated in subsequent years (2017-2019) following environmental management changes. Notably, this study demonstrates that domestic large animals such as horses can serve as important sentinels for human health risks associated with UNGD activities.

%B Sci Total Environ %V 731 %P 138497 %8 2020 Aug 20 %G eng %R 10.1016/j.scitotenv.2020.138497 %0 Generic %D 2020 %T A Novel Approach to Forming Sufficiently Similar Mixtures From Environmental Exposure Data %A Briana N Rivera %A Christine C Ghetu %A Kaley A Adams %A Kim A Anderson %A Susan C Tilton %B Pacific Northwest Association of Toxicologists Annual Meeting %8 11/2020 %G eng %0 Audiovisual Material %D 2020 %T A Novel Approach to Forming Sufficiently Similar Mixtures from Environmental Exposure Data %A Briana N Rivera %A Christine C Ghetu %A Kim A Anderson %A Susan C Tilton %B Superfund Research Center Annual Meeting %8 12/2020 %G eng %0 Generic %D 2020 %T Superfund Research Program (SRP) Karen Wetterhahn Award Nominee %A Briana N Rivera %8 07/2020 %G eng %0 Generic %D 2020 %T Time-Integrated Exposures to Identify Chemical Profiles between Health and Dysphagic Foals %A Briana N Rivera %E K. Mullen %Y Lane G Tidwell %? R. Ivanek %? D. Ainsworth %? Kim A Anderson %B Society of Toxicology %8 03/2020 %G eng %0 Audiovisual Material %D 2019 %T Determining Environmental Exposure Profiles of Health and Dysphagic Foals %A Briana N Rivera %A Kathleen Mullen %A Lane G Tidwell %A Renata Ivanek %A Dorothy Ainsworth %A Susan C Tilton %A Kim A Anderson %B Society of Environmental Toxicology and Chemistry North America, Toronto, ON %8 11/2019 %G eng %0 Audiovisual Material %D 2019 %T Determining Environmental Exposure Profiles of Health and Dysphagic Foals %A Briana N Rivera %A Kathleen Mullen %A Lane G Tidwell %A Renata Ivanek %A Dorothy Ainsworth %A Susan C Tilton %A Kim A Anderson %B Superfund Research Program, Seattle, WA %8 11/2019 %G eng %0 Audiovisual Material %D 2019 %T Evaluating Toxicity of Inhalation Exposure to Unconventional Natural Gas Drilling %A Briana N Rivera %A Lane G Tidwell %A Carey E Donald %A Yvonne Chang %A Kathleen Mullen %A Dorothy Ainsworth %A Kim A Anderson %A Susan C Tilton %B Society of Toxicology National Conference, Baltimore, MD %8 03/2019 %G eng %0 Audiovisual Material %D 2019 %T Evaluating Toxicity of Inhalation Exposure to Unconventional Natural Gas Drilling %A Briana N Rivera %A Lane G Tidwell %A Carey E Donald %A Yvonne Chang %A Kathleen Mullen %A Dorothy Ainsworth %A Kim A Anderson %A Susan C Tilton %B Society of Toxicology National Conference, Baltimore, MD %8 03/2019 %G eng %0 Generic %D 2019 %T How Should We Approach Forming Representative Mixtures? %A Briana N Rivera %A Kim A Anderson %A Susan C Tilton %B Environmental Health Sciences Colloquim, Corvallis OR %8 09/2019 %G eng %0 Generic %D 2019 %T Oregon Museum of Science and Industry (OMSI) inclusivity, diversity, equitability, and accessibility (IDEA) Scholarship %A Briana N Rivera %8 11/2019 %G eng %0 Generic %D 2019 %T Society of Environmental Toxicology and Chemistry (SETAC) North America Student Travel Award %A Briana N Rivera %B SETAC %8 11/2019 %G eng %0 Generic %D 2019 %T Society of Environmental Toxicology and Chemistry (SETAC) Travel Award %A Briana N Rivera %8 11/2019 %G eng %0 Generic %D 2019 %T Using Passive Samplers to Evaluate Inhalation Exposure %A Briana N Rivera %A Kathleen Mullen %A Lane G Tidwell %A Renata Ivanek %A Dorothy Ainsworth %A Susan C Tilton %A Kim A Anderson %B Military Health System Research Symposium, Kissimmee, FL %8 08/2019 %G eng %0 Audiovisual Material %D 2018 %T Evaluating Toxicity Associated with Inhalation Exposure to Unconventional Natural Gas Drilling %A Briana N Rivera %A Lane G Tidwell %A Yvonne Chang %A Carey E Donald %A Kathleen Mullen %A Dorothy Ainsworth %A Richard P Scott %A Kim A Anderson %A Susan C Tilton %B Environmental Public Health in the 21st Century Research Symposium %8 01/2018 %G eng %0 Generic %D 2018 %T Training Grant Fellowship for Graduate Research & Education %A Briana N Rivera %B National Institute of Environmental Health Sciences %8 01/2018 %G eng %0 Audiovisual Material %D 2018 %T Using passive samplers and 3D bronchial epithelium to determine toxicity associated with natural gas drilling %A Briana N Rivera %A Lane G Tidwell %A Carey E Donald %A Kathleen Mullen %A Dorothy Ainsworth %A Richard P Scott %A Kim A Anderson %A Susan C Tilton %B Pacific Northwest Association of Toxicologists (PANWAT), Bothell, Wa %8 10/2018 %G eng %0 Audiovisual Material %D 2018 %T Using passive samplers and 3D bronchial epithelium to determine toxicity associated with natural gas drilling %A Briana N Rivera %A Lane G Tidwell %A Carey E Donald %A Kathleen Mullen %A Dorothy Ainsworth %A Richard P Scott %A Kim A Anderson %A Susan C Tilton %B Center for Genome Research and Biocomputing Fall Conference %8 10/2018 %G eng %0 Generic %D 2017 %T Training Grant Fellowship for Graduate Research & Education %A Briana N Rivera %B National Institute of Environmental Health Sciences %8 01/2018 %G eng